COMPARISON
Bremelanotide vs Icatibant
5 attributes held for at least one of the two. 5 differ. Each value carries the register it came from and the date that register was read.
Answer
Bremelanotide is authorised or registered in 1 and Icatibant in 10 of the 10 registers read. Bremelanotide: highest phase Phase 2. Icatibant: highest phase Phase 3 (3 phase 3 trials, 0 with posted results). 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Bremelanotide | Icatibant | |
|---|---|---|
| Registered trials differs | 10 clinicaltrials.gov · 2026-10-03 | 37 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA-approved: Vyleesi openfda · 2026-10-03T17:23:44.062Z | FDA-approved: SAJAZIR openfda · 2026-10-03T17:23:44.062Z |
| EU authorisation differs | Nothing on record ema read 2026-08-31 | Authorised ema · 2026-10-03 |
| EU authorised on differs | Not checked no record of "authorisedOn" for bremelanotide | 2008-07-11 ema · 2026-10-03 |
| ATC code differs | Not checked no record of "atcCode" for bremelanotide | B06AC02 ema · 2026-10-03 |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Bremelanotide | placebo | Icatibant | placebo |
|---|---|---|---|---|
| Headache | 10.7% | 6.5% | 10.1% | 6.7% |
| Nausea | 33.6% | 17.7% | - | - |
| Flushing | 17.9% | 9.4% | - | - |
| Sunburn | 6.8% | 11.3% | - | - |
| Upper respiratory tract infection | 5.8% | 5.8% | - | - |
| Injection site pain | 5.1% | 5.7% | - | - |
| Injection site reaction | 4.5% | 2.1% | - | - |
| Urinary tract infection | 4.3% | 4.2% | - | - |
| Vomiting | 4.1% | 2.2% | - | - |
| Nasopharyngitis | 3.3% | 3.4% | - | - |
| Hereditary angioedema | - | - | 18.1% | 18.7% |
Trial register Bremelanotide: 4 placebo-controlled trials; Icatibant: 4. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Bremelanotide side effects · Icatibant side effects
LEGAL STATUS
Approval in each country read
| Country | Bremelanotide | Icatibant | Register |
|---|---|---|---|
| United States | FDA-approved | FDA-approved | Regulator FDA |
| European Union | Not on the register | Authorised | Regulator EMA |
| United Kingdom | Not on the register | Authorised | Regulator MHRA |
| Canada | Not on the register | Authorised | Regulator Health Canada |
| Australia | Status unknown | Registered | TGA |
| Switzerland | Not on the register | Authorised | Regulator Swissmedic |
| Brazil | Not on the register | Registado | Regulator ANVISA |
| Serbia | Not on the register | Authorised | Regulator ALIMS |
| Singapore | Not on the register | Registered | Regulator HSA |
| Turkey | Not on the register | Ruhsatli | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
WEEKLY
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New trials, approvals and enforcement actions. One email a week.