COMPARISON
Cagrilintide vs Retatrutide
2 attributes held for at least one of the two. 1 differ. Each value carries the register it came from and the date that register was read.
Answer
Cagrilintide is authorised or registered in 0 and Retatrutide in 0 of the 10 registers read. Cagrilintide: highest phase Phase 3 (17 phase 3 trials, 0 with posted results). Retatrutide: highest phase Phase 3 (20 phase 3 trials, 0 with posted results). 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Cagrilintide | Retatrutide | |
|---|---|---|
| Registered trials differs | 66 clinicaltrials.gov · 2026-10-03 | 41 clinicaltrials.gov · 2026-10-03 |
| EU authorisation | Nothing on record ema read 2026-08-31 | Nothing on record ema read 2026-08-31 |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Cagrilintide | placebo | Retatrutide | placebo |
|---|---|---|---|---|
| Nausea | 29.0% | 14.8% | 26.0% | 8.7% |
| COVID-19 | 16.1% | 13.1% | 14.9% | 14.8% |
| Constipation | 16.1% | 13.1% | 10.7% | 2.6% |
| Diarrhoea | 16.1% | 6.6% | 14.2% | 8.7% |
| Fatigue | 9.7% | 1.6% | 6.6% | 2.6% |
| Gastrooesophageal reflux disease | 9.7% | 1.6% | 4.9% | 1.4% |
| Vomiting | 9.7% | 1.6% | 10.1% | 1.7% |
| Back pain | 6.5% | 3.3% | - | - |
| Eructation | 6.5% | 0.0% | - | - |
| Gastroenteritis | 6.5% | 6.6% | - | - |
| Decreased appetite | - | - | 17.9% | 5.2% |
| Lipase increased | - | - | 5.5% | 3.5% |
| Hypertension | - | - | 5.2% | 2.9% |
Trial register Cagrilintide: 1 placebo-controlled trials; Retatrutide: 2. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Cagrilintide side effects · Retatrutide side effects
LEGAL STATUS
Approval in each country read
| Country | Cagrilintide | Retatrutide | Register |
|---|---|---|---|
| United States | Not on the register | Not on the register | Regulator FDA |
| European Union | Not on the register | Not on the register | Regulator EMA |
| United Kingdom | Not on the register | Not on the register | Regulator MHRA |
| Canada | Not on the register | Not on the register | Regulator Health Canada |
| Australia | Status unknown | Status unknown | TGA |
| Switzerland | Not on the register | Not on the register | Regulator Swissmedic |
| Brazil | Not on the register | Not on the register | Regulator ANVISA |
| Serbia | Not on the register | Not on the register | Regulator ALIMS |
| Singapore | Not on the register | Not on the register | Regulator HSA |
| Turkey | Not on the register | Not on the register | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
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