COMPARISON

Carfilzomib vs Octreotide

6 attributes held for at least one of the two. 5 differ. Each value carries the register it came from and the date that register was read.

Answer

Carfilzomib is authorised or registered in 10 and Octreotide in 10 of the 10 registers read. Carfilzomib: highest phase Phase 3 (14 phase 3 trials, 0 with posted results). Octreotide: highest phase Phase 4 (after approval). 0 registered trials include both.

States no view on which is preferable, safer or more effective. Not medical advice.

CarfilzomibOctreotide
Registered trials
differs
308
clinicaltrials.gov · 2026-10-03
344
clinicaltrials.gov · 2026-10-03
FDA label
differs
FDA-approved: KYPROLIS
openfda · 2026-10-03T17:23:44.062Z
FDA-approved: Octreotide Acetate
openfda · 2026-10-03T17:23:44.062Z
EU authorisation
Authorised
ema · 2026-10-03
Authorised
ema · 2026-10-03
EU authorised on
differs
2015-11-19
ema · 2026-10-03
2025-06-30
ema · 2026-10-03
EU withdrawn on
differs
Not checked
no record of "withdrawnOn" for carfilzomib
2022-12-02
ema · 2026-10-03
ATC code
differs
L01XX45
ema · 2026-10-03
H01CB02
ema · 2026-10-03

SIDE EFFECTS

Most common side effects, each beside its own placebo

Side effectCarfilzomibplaceboOctreotideplacebo
Diarrhoea--46.2%31.7%
Oedema peripheral--34.9%19.6%
Asthenia--33.3%20.9%
Nausea--30.8%21.2%
Fatigue--29.8%27.7%
Rash--28.8%14.1%
Decreased appetite--28.5%15.2%
Hypertension--26.5%19.4%
Dyspnoea--25.9%9.1%
Anaemia--24.3%9.1%

Trial register Carfilzomib: 0 placebo-controlled trials; Octreotide: 5. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Carfilzomib side effects · Octreotide side effects

LEGAL STATUS

Approval in each country read

CountryCarfilzomibOctreotideRegister
United StatesFDA-approvedFDA-approvedRegulator FDA
European UnionAuthorisedAuthorisedRegulator EMA
United KingdomAuthorisedAuthorisedRegulator MHRA
CanadaAuthorisedAuthorisedRegulator Health Canada
AustraliaRegisteredRegisteredRegulator TGA
SwitzerlandAuthorisedAuthorisedRegulator Swissmedic
BrazilRegistadoRegistadoRegulator ANVISA
SerbiaAuthorisedAuthorisedRegulator ALIMS
SingaporeRegisteredRegisteredRegulator HSA
TurkeyRuhsatliRuhsatliRegulator TITCK

Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.

WEEKLY

Register Watch, weekly

New trials, approvals and enforcement actions. One email a week.