COMPARISON
Ciclosporin vs Tirzepatide
5 attributes held for at least one of the two. 4 differ. Each value carries the register it came from and the date that register was read.
Answer
Ciclosporin is authorised or registered in 9 and Tirzepatide in 10 of the 10 registers read. Ciclosporin: highest phase Phase 4 (after approval). Tirzepatide: highest phase Phase 4 (after approval). 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Ciclosporin | Tirzepatide | |
|---|---|---|
| Registered trials differs | 1328 clinicaltrials.gov · 2026-10-03 | 309 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA label, application not recorded: VEVYE openfda · 2026-08-31T07:37:14Z | FDA-approved: MOUNJARO openfda · 2026-10-03T17:23:44.062Z |
| EU authorisation | Authorised ema · 2026-10-03 | Authorised ema · 2026-10-03 |
| EU authorised on differs | 2015-03-19 ema · 2026-10-03 | 2022-09-15 ema · 2026-10-03 |
| ATC code differs | S01XA18 ema · 2026-10-03 | A10BX16 ema · 2026-10-03 |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Ciclosporin | placebo | Tirzepatide | placebo |
|---|---|---|---|---|
| Punctate Keratitis | 5.8% | 4.5% | - | - |
| Nausea | - | - | 25.6% | 8.1% |
| Diarrhoea | - | - | 21.2% | 8.3% |
| Covid-19 | - | - | 15.5% | 16.0% |
| Constipation | - | - | 13.7% | 4.5% |
| Decreased appetite | - | - | 11.6% | 2.9% |
| Vomiting | - | - | 11.4% | 2.6% |
| Dyspepsia | - | - | 7.9% | 2.7% |
| Headache | - | - | 6.6% | 6.2% |
| Abdominal pain | - | - | 6.0% | 2.7% |
| Upper respiratory tract infection | - | - | 5.7% | 6.2% |
Trial register Ciclosporin: 7 placebo-controlled trials; Tirzepatide: 19. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Ciclosporin side effects · Tirzepatide side effects
LEGAL STATUS
Approval in each country read
| Country | Ciclosporin | Tirzepatide | Register |
|---|---|---|---|
| United States | FDA label, application not recorded | FDA-approved | Regulator FDA |
| European Union | Authorised | Authorised | Regulator EMA |
| United Kingdom | Authorised | Authorised | Regulator MHRA |
| Canada | Authorised | Authorised | Regulator Health Canada |
| Australia | Registered | Registered | Regulator TGA |
| Switzerland | Authorised | Authorised | Regulator Swissmedic |
| Brazil | Registado | Registado | Regulator ANVISA |
| Serbia | Authorised | Authorised | Regulator ALIMS |
| Singapore | Registered | Registered | Regulator HSA |
| Turkey | Ruhsatli | Ruhsatli | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
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New trials, approvals and enforcement actions. One email a week.