COMPARISON
Desmopressin vs Tesamorelin
3 attributes held for at least one of the two. 3 differ. Each value carries the register it came from and the date that register was read.
Answer
Desmopressin is authorised or registered in 9 and Tesamorelin in 2 of the 10 registers read. Desmopressin: highest phase Phase 4 (after approval). Tesamorelin: No trial states a phase. 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Desmopressin | Tesamorelin | |
|---|---|---|
| Registered trials differs | 131 clinicaltrials.gov · 2026-10-03 | 24 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA-approved: Desmopressin Acetate openfda · 2026-10-03T17:23:44.062Z | FDA-approved: EGRIFTA SV openfda · 2026-10-03T17:23:44.062Z |
| EU authorisation differs | Nothing on record ema read 2026-08-31 | Application withdrawn ema · 2026-10-03 |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Desmopressin | placebo | Tesamorelin | placebo |
|---|---|---|---|---|
| Headache | 7.0% | 3.9% | - | - |
| Nausea | 4.9% | 1.3% | - | - |
| Diarrhoea | 4.7% | 2.2% | - | - |
| Nasopharyngitis | 4.2% | 3.1% | - | - |
| Hypertension | 3.3% | 0.7% | - | - |
| Dizziness | 3.2% | 0.4% | - | - |
| Hyponatraemia | 3.1% | 1.2% | - | - |
| Pneumonia | 0.1% | 0.0% | - | - |
| Depression | 0.1% | 0.4% | - | - |
| Diverticulitis | 0.1% | 0.0% | - | - |
| Injection site erythema | - | - | 6.8% | 2.6% |
| Paresthesia | - | - | 2.4% | 5.0% |
| Injection site pain | - | - | 1.8% | 2.5% |
| Nephrolithiasis | - | - | 0.8% | 0.5% |
| Abdominal pain | - | - | 0.6% | 1.5% |
Trial register Desmopressin: 8 placebo-controlled trials; Tesamorelin: 4. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Desmopressin side effects · Tesamorelin side effects
LEGAL STATUS
Approval in each country read
| Country | Desmopressin | Tesamorelin | Register |
|---|---|---|---|
| United States | FDA-approved | FDA-approved | Regulator FDA |
| European Union | Not on the register | Application withdrawn | Regulator EMA |
| United Kingdom | Authorised | Not on the register | Regulator MHRA |
| Canada | Authorised | Authorised | Regulator Health Canada |
| Australia | Registered | Status unknown | Regulator TGA |
| Switzerland | Authorised | Not on the register | Regulator Swissmedic |
| Brazil | Registado | Not on the register | Regulator ANVISA |
| Serbia | Authorised | Not on the register | Regulator ALIMS |
| Singapore | Registered | Not on the register | Regulator HSA |
| Turkey | Ruhsatli | Not on the register | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
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