COMPARISON
Dulaglutide vs Pramlintide
5 attributes held for at least one of the two. 5 differ. Each value carries the register it came from and the date that register was read.
Answer
Dulaglutide is authorised or registered in 10 and Pramlintide in 1 of the 10 registers read. Dulaglutide: highest phase Phase 4 (after approval). Pramlintide: highest phase Phase 3 (1 phase 3 trial, 0 with posted results). 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Dulaglutide | Pramlintide | |
|---|---|---|
| Registered trials differs | 144 clinicaltrials.gov · 2026-10-03 | 65 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA-approved: TRULICITY openfda · 2026-10-03T17:23:44.062Z | FDA-approved: SymlinPen openfda · 2026-10-03T17:23:44.062Z |
| EU authorisation differs | Authorised ema · 2026-10-03 | Nothing on record ema read 2026-08-31 |
| EU authorised on differs | 2014-11-21 ema · 2026-10-03 | Not checked no record of "authorisedOn" for pramlintide |
| ATC code differs | A10BJ05 ema · 2026-10-03 | Not checked no record of "atcCode" for pramlintide |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Dulaglutide | placebo | Pramlintide | placebo |
|---|---|---|---|---|
| Nausea | 14.5% | 5.5% | 28.5% | 4.7% |
| Nasopharyngitis | 11.2% | 10.4% | 6.6% | 7.5% |
| Diarrhoea | 12.8% | 8.5% | - | - |
| Urinary tract infection | 10.2% | 9.8% | - | - |
| Back pain | 8.4% | 7.9% | - | - |
| Bronchitis | 7.9% | 8.3% | - | - |
| Hypoglycaemia | 7.5% | 6.6% | - | - |
| Arthralgia | 7.3% | 7.6% | - | - |
| Constipation | 7.2% | 4.1% | - | - |
| Decreased appetite | 7.1% | 2.2% | - | - |
| injection site pruritus | - | - | 14.7% | 0.7% |
| injection site erythema | - | - | 14.5% | 0.9% |
| Upper respiratory tract infection | - | - | 12.1% | 10.4% |
| injection site bruising | - | - | 11.2% | 12.3% |
| injection site hemorrhage | - | - | 11.2% | 3.8% |
| injection site rash | - | - | 8.9% | 0.0% |
| injection site urticaria | - | - | 8.3% | 0.0% |
| injection site nodule | - | - | 5.9% | 3.8% |
Trial register Dulaglutide: 11 placebo-controlled trials; Pramlintide: 5. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Dulaglutide side effects · Pramlintide side effects
LEGAL STATUS
Approval in each country read
| Country | Dulaglutide | Pramlintide | Register |
|---|---|---|---|
| United States | FDA-approved | FDA-approved | Regulator FDA |
| European Union | Authorised | Not on the register | Regulator EMA |
| United Kingdom | Authorised | Not on the register | Regulator MHRA |
| Canada | Authorised | Not on the register | Regulator Health Canada |
| Australia | Registered | Status unknown | Regulator TGA |
| Switzerland | Authorised | Not on the register | Regulator Swissmedic |
| Brazil | Registado | Not on the register | Regulator ANVISA |
| Serbia | Authorised | Not on the register | Regulator ALIMS |
| Singapore | Registered | Not on the register | Regulator HSA |
| Turkey | Ruhsatli | Not on the register | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
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