COMPARISON
Goserelin vs Semaglutide
5 attributes held for at least one of the two. 5 differ. Each value carries the register it came from and the date that register was read.
Answer
Goserelin is authorised or registered in 9 and Semaglutide in 10 of the 10 registers read. Goserelin: highest phase Phase 4 (after approval). Semaglutide: highest phase Phase 4 (after approval). 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Goserelin | Semaglutide | |
|---|---|---|
| Registered trials differs | 449 clinicaltrials.gov · 2026-10-03 | 861 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA-approved: ZOLADEX openfda · 2026-10-03T17:23:44.062Z | FDA-approved: OZEMPIC openfda · 2026-10-03T17:23:44.062Z |
| EU authorisation differs | Nothing on record ema read 2026-08-31 | Authorised ema · 2026-10-03 |
| EU authorised on differs | Not checked no record of "authorisedOn" for goserelin | 2018-02-08 ema · 2026-10-03 |
| ATC code differs | Not checked no record of "atcCode" for goserelin | A10BJ06 ema · 2026-10-03 |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Goserelin | placebo | Semaglutide | placebo |
|---|---|---|---|---|
| Diarrhoea | 24.5% | 19.9% | 11.8% | 4.5% |
| Nausea | 23.1% | 19.1% | 19.5% | 4.5% |
| Neutropenia | 57.9% | 6.5% | - | - |
| Arthralgia | 38.8% | 36.2% | - | - |
| Neutrophil count decreased | 35.5% | 1.5% | - | - |
| Hot flush | 35.2% | 34.7% | - | - |
| Fatigue | 26.6% | 25.5% | - | - |
| Back pain | 22.7% | 21.4% | - | - |
| Anaemia | 21.8% | 11.0% | - | - |
| Leukopenia | 19.7% | 3.9% | - | - |
| COVID-19 | - | - | 17.0% | 17.8% |
| Constipation | - | - | 8.9% | 2.8% |
| Vomiting | - | - | 8.6% | 1.6% |
| Nasopharyngitis | - | - | 7.5% | 6.1% |
| Decreased appetite | - | - | 6.3% | 1.3% |
| Dyspepsia | - | - | 5.3% | 1.2% |
| Headache | - | - | 4.0% | 2.1% |
| Upper respiratory tract infection | - | - | 2.7% | 1.9% |
Trial register Goserelin: 2 placebo-controlled trials; Semaglutide: 50. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Goserelin side effects · Semaglutide side effects
LEGAL STATUS
Approval in each country read
| Country | Goserelin | Semaglutide | Register |
|---|---|---|---|
| United States | FDA-approved | FDA-approved | Regulator FDA |
| European Union | Not on the register | Authorised | Regulator EMA |
| United Kingdom | Authorised | Authorised | Regulator MHRA |
| Canada | Authorised | Authorised | Regulator Health Canada |
| Australia | Registered | Registered | Regulator TGA |
| Switzerland | Authorised | Authorised | Regulator Swissmedic |
| Brazil | Registado | Registado | Regulator ANVISA |
| Serbia | Authorised | Authorised | Regulator ALIMS |
| Singapore | Registered | Registered | Regulator HSA |
| Turkey | Ruhsatli | Ruhsatli | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
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