COMPARISON
Goserelin vs Triptorelin
3 attributes held for at least one of the two. 3 differ. Each value carries the register it came from and the date that register was read.
Answer
Goserelin is authorised or registered in 9 and Triptorelin in 10 of the 10 registers read. Goserelin: highest phase Phase 4 (after approval). Triptorelin: highest phase Phase 4 (after approval). 82 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Goserelin | Triptorelin | |
|---|---|---|
| Registered trials differs | 449 clinicaltrials.gov · 2026-10-03 | 317 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA-approved: ZOLADEX openfda · 2026-10-03T17:23:44.062Z | FDA-approved: Trelstar openfda · 2026-10-03T17:23:44.062Z |
| EU authorisation differs | Nothing on record ema read 2026-08-31 | Authorised ema · 2026-08-31 |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Goserelin | placebo | Triptorelin | placebo |
|---|---|---|---|---|
| Neutropenia | 57.9% | 6.5% | - | - |
| Arthralgia | 38.8% | 36.2% | - | - |
| Neutrophil count decreased | 35.5% | 1.5% | - | - |
| Hot flush | 35.2% | 34.7% | - | - |
| Fatigue | 26.6% | 25.5% | - | - |
| Diarrhoea | 24.5% | 19.9% | - | - |
| Nausea | 23.1% | 19.1% | - | - |
| Back pain | 22.7% | 21.4% | - | - |
| Anaemia | 21.8% | 11.0% | - | - |
| Leukopenia | 19.7% | 3.9% | - | - |
Trial register Goserelin: 2 placebo-controlled trials; Triptorelin: 0. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Goserelin side effects · Triptorelin side effects
LEGAL STATUS
Approval in each country read
| Country | Goserelin | Triptorelin | Register |
|---|---|---|---|
| United States | FDA-approved | FDA-approved | Regulator FDA |
| European Union | Not on the register | Authorised | Regulator EMA |
| United Kingdom | Authorised | Authorised | Regulator MHRA |
| Canada | Authorised | Authorised | Regulator Health Canada |
| Australia | Registered | Registered | Regulator TGA |
| Switzerland | Authorised | Authorised | Regulator Swissmedic |
| Brazil | Registado | Registado | Regulator ANVISA |
| Serbia | Authorised | Authorised | Regulator ALIMS |
| Singapore | Registered | Registered | Regulator HSA |
| Turkey | Ruhsatli | Ruhsatli | Regulator TITCK |
HEAD TO HEAD
82 registered trials include both
| 2022-501024-20-00 | CAMBRIA-1: A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Extended Therapy With Camizestrant (AZD9833, a Next Generation, Oral S Not stated · updated 2026-09-29 |
|---|---|
| 2024-519655-28-00 | OPTIMA YOUNG : Optimal Personalized Treatment of early breast cancer using Multi-parameter Analysis : focus on YOUNGer women Not stated · updated 2026-09-14 |
| 2023-509494-23-00 | DARIUS : A RANDOMIZED NON-COMPARATIVE PHASE II MULTICENTRIC TRIAL ON SHORT TERM DAROLUTAMIDE (ODM-201) CONCOMITANT TO RADIATION THERAPY FOR PATIENTS WITH INTERM Not stated · updated 2026-09-07 |
| NCT04557059 | A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer ACTIVE_NOT_RECRUITING · updated 2026-08-28 |
| NCT07782840 | QL1706 Plus Neoadjuvant Endocrine Therapy in HR-Positive/HER2-Negative Breast Cancer With a Poor Response to Neoadjuvant Chemotherapy NOT_YET_RECRUITING · updated 2026-08-26 |
| NCT04423211 | Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging RECRUITING · updated 2026-08-19 |
| NCT04513717 | Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatm ACTIVE_NOT_RECRUITING · updated 2026-08-17 |
| NCT05050084 | Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a ACTIVE_NOT_RECRUITING · updated 2026-08-17 |
| NCT03332797 | A Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing Hormone-Releasing Hormone (LHRH) Agonist in Locally Advanced or Metastatic Estro ACTIVE_NOT_RECRUITING · updated 2026-08-13 |
| NCT07751133 | Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer NOT_YET_RECRUITING · updated 2026-08-07 |
| NCT05879926 | Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-N RECRUITING · updated 2026-08-04 |
| NCT07340619 | Clinical Trial Evaluating the Biological Activity of a New Drug Identified as Prifetrastat (PF-07248144), Combined With Fulvestrant for the Treatment of Patient NOT_YET_RECRUITING · updated 2026-08-03 |
| NCT04484818 | Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICAT ACTIVE_NOT_RECRUITING · updated 2026-07-28 |
| NCT07730151 | Efficacy and Safety of Darolutamide Combined With Docetaxel and ADT as Neoadjuvant Therapy for Locally Advanced Prostate Cancer. NOT_YET_RECRUITING · updated 2026-07-28 |
| NCT06378866 | Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy RECRUITING · updated 2026-07-20 |
| NCT05498272 | Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select H ACTIVE_NOT_RECRUITING · updated 2026-07-10 |
| NCT02346253 | High-Dose Brachytherapy in Treating Patients With Prostate Cancer COMPLETED · updated 2026-07-02 |
| NCT06922318 | The COSMYC Trial (COmbined Suppression of MYC) RECRUITING · updated 2026-06-18 |
| NCT04961996 | A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estr ACTIVE_NOT_RECRUITING · updated 2026-06-17 |
| NCT07477626 | Radiotherapy After Prostatectomy for Node Positive Prostate Cancer RECRUITING · updated 2026-06-16 |
The 20 most recently updated are listed.
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
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