COMPARISON
Icatibant vs Melanotan II
5 attributes held for at least one of the two. 5 differ. Each value carries the register it came from and the date that register was read.
Answer
Icatibant is authorised or registered in 10 and Melanotan II in 0 of the 10 registers read. Icatibant: highest phase Phase 3 (3 phase 3 trials, 0 with posted results). Melanotan II: No trial states a phase. 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Icatibant | Melanotan II | |
|---|---|---|
| Registered trials differs | 37 clinicaltrials.gov · 2026-10-03 | 26 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA-approved: SAJAZIR openfda · 2026-10-03T17:23:44.062Z | Not checked no record of "fdaLabel" for melanotan-ii |
| EU authorisation differs | Authorised ema · 2026-10-03 | Nothing on record ema read 2026-08-31 |
| EU authorised on differs | 2008-07-11 ema · 2026-10-03 | Not checked no record of "authorisedOn" for melanotan-ii |
| ATC code differs | B06AC02 ema · 2026-10-03 | Not checked no record of "atcCode" for melanotan-ii |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Icatibant | placebo | Melanotan II | placebo |
|---|---|---|---|---|
| Hereditary angioedema | 18.1% | 18.7% | - | - |
| Headache | 10.1% | 6.7% | - | - |
Trial register Icatibant: 4 placebo-controlled trials; Melanotan II: 0. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Icatibant side effects · Melanotan II side effects
LEGAL STATUS
Approval in each country read
| Country | Icatibant | Melanotan II | Register |
|---|---|---|---|
| United States | FDA-approved | Not on the register | Regulator FDA |
| European Union | Authorised | Not on the register | Regulator EMA |
| United Kingdom | Authorised | Not on the register | Regulator MHRA |
| Canada | Authorised | Not on the register | Regulator Health Canada |
| Australia | Registered | Status unknown | Regulator TGA |
| Switzerland | Authorised | Not on the register | Regulator Swissmedic |
| Brazil | Registado | Not on the register | Regulator ANVISA |
| Serbia | Authorised | Not on the register | Regulator ALIMS |
| Singapore | Registered | Not on the register | Regulator HSA |
| Turkey | Ruhsatli | Not on the register | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
WEEKLY
Register Watch, weekly
New trials, approvals and enforcement actions. One email a week.