COMPARISON
Icatibant vs SS-31 (elamipretide)
5 attributes held for at least one of the two. 5 differ. Each value carries the register it came from and the date that register was read.
Answer
Icatibant is authorised or registered in 10 and SS-31 (elamipretide) in 0 of the 10 registers read. Icatibant: highest phase Phase 3 (3 phase 3 trials, 0 with posted results). SS-31 (elamipretide): No trial states a phase. 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Icatibant | SS-31 (elamipretide) | |
|---|---|---|
| Registered trials differs | 37 clinicaltrials.gov · 2026-10-03 | 30 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA-approved: SAJAZIR openfda · 2026-10-03T17:23:44.062Z | Not checked no record of "fdaLabel" for ss-31 |
| EU authorisation differs | Authorised ema · 2026-10-03 | Nothing on record ema read 2026-08-31 |
| EU authorised on differs | 2008-07-11 ema · 2026-10-03 | Not checked no record of "authorisedOn" for ss-31 |
| ATC code differs | B06AC02 ema · 2026-10-03 | Not checked no record of "atcCode" for ss-31 |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Icatibant | placebo | SS-31 (elamipretide) | placebo |
|---|---|---|---|---|
| Headache | 10.1% | 6.7% | 4.4% | 3.4% |
| Hereditary angioedema | 18.1% | 18.7% | - | - |
| Injection site erythema | - | - | 63.8% | 44.7% |
| Injection site pain | - | - | 29.4% | 21.8% |
| Nasopharyngitis | - | - | 5.5% | 2.4% |
| Nausea | - | - | 4.8% | 4.7% |
| Fall | - | - | 4.3% | 4.7% |
| Hypertension | - | - | 3.7% | 2.7% |
| Dizziness | - | - | 3.1% | 2.5% |
| Cough | - | - | 3.0% | 2.2% |
| Urinary Tract Infection | - | - | 2.9% | 2.3% |
Trial register Icatibant: 4 placebo-controlled trials; SS-31 (elamipretide): 5. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Icatibant side effects · SS-31 (elamipretide) side effects
LEGAL STATUS
Approval in each country read
| Country | Icatibant | SS-31 (elamipretide) | Register |
|---|---|---|---|
| United States | FDA-approved | Not on the register | Regulator FDA |
| European Union | Authorised | Not on the register | Regulator EMA |
| United Kingdom | Authorised | Not on the register | Regulator MHRA |
| Canada | Authorised | Not on the register | Regulator Health Canada |
| Australia | Registered | Status unknown | Regulator TGA |
| Switzerland | Authorised | Not on the register | Regulator Swissmedic |
| Brazil | Registado | Not on the register | Regulator ANVISA |
| Serbia | Authorised | Not on the register | Regulator ALIMS |
| Singapore | Registered | Not on the register | Regulator HSA |
| Turkey | Ruhsatli | Not on the register | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
WEEKLY
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New trials, approvals and enforcement actions. One email a week.