COMPARISON
Liraglutide vs Octreotide
6 attributes held for at least one of the two. 5 differ. Each value carries the register it came from and the date that register was read.
Answer
Liraglutide is authorised or registered in 10 and Octreotide in 10 of the 10 registers read. Liraglutide: highest phase Phase 4 (after approval). Octreotide: highest phase Phase 4 (after approval). 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Liraglutide | Octreotide | |
|---|---|---|
| Registered trials differs | 518 clinicaltrials.gov · 2026-10-03 | 344 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA-approved: Liraglutide openfda · 2026-10-03T17:23:44.062Z | FDA-approved: Octreotide Acetate openfda · 2026-10-03T17:23:44.062Z |
| EU authorisation | Authorised ema · 2026-10-03 | Authorised ema · 2026-10-03 |
| EU authorised on differs | 2009-06-30 ema · 2026-10-03 | 2025-06-30 ema · 2026-10-03 |
| EU withdrawn on differs | Not checked no record of "withdrawnOn" for liraglutide | 2022-12-02 ema · 2026-10-03 |
| ATC code differs | A10BJ02 ema · 2026-10-03 | H01CB02 ema · 2026-10-03 |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Liraglutide | placebo | Octreotide | placebo |
|---|---|---|---|---|
| Nausea | 26.4% | 7.4% | 30.8% | 21.2% |
| Diarrhoea | 13.1% | 6.1% | 46.2% | 31.7% |
| Decreased appetite | 6.6% | 1.2% | 28.5% | 15.2% |
| Nasopharyngitis | 12.4% | 9.3% | - | - |
| Vomiting | 9.0% | 2.1% | - | - |
| Constipation | 8.8% | 3.1% | - | - |
| Hypoglycaemia | 8.7% | 3.3% | - | - |
| Headache | 8.3% | 5.9% | - | - |
| Upper respiratory tract infection | 6.0% | 4.7% | - | - |
| Dyspepsia | 5.3% | 1.3% | - | - |
| Oedema peripheral | - | - | 34.9% | 19.6% |
| Asthenia | - | - | 33.3% | 20.9% |
| Fatigue | - | - | 29.8% | 27.7% |
| Rash | - | - | 28.8% | 14.1% |
| Hypertension | - | - | 26.5% | 19.4% |
| Dyspnoea | - | - | 25.9% | 9.1% |
| Anaemia | - | - | 24.3% | 9.1% |
Trial register Liraglutide: 42 placebo-controlled trials; Octreotide: 5. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Liraglutide side effects · Octreotide side effects
LEGAL STATUS
Approval in each country read
| Country | Liraglutide | Octreotide | Register |
|---|---|---|---|
| United States | FDA-approved | FDA-approved | Regulator FDA |
| European Union | Authorised | Authorised | Regulator EMA |
| United Kingdom | Authorised | Authorised | Regulator MHRA |
| Canada | Authorised | Authorised | Regulator Health Canada |
| Australia | Registered | Registered | Regulator TGA |
| Switzerland | Authorised | Authorised | Regulator Swissmedic |
| Brazil | Registado | Registado | Regulator ANVISA |
| Serbia | Authorised | Authorised | Regulator ALIMS |
| Singapore | Registered | Registered | Regulator HSA |
| Turkey | Ruhsatli | Ruhsatli | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
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