COMPARISON
Oxytocin vs Terlipressin
3 attributes held for at least one of the two. 2 differ. Each value carries the register it came from and the date that register was read.
Answer
Oxytocin is authorised or registered in 9 and Terlipressin in 8 of the 10 registers read. Oxytocin: highest phase Phase 4 (after approval). Terlipressin: highest phase Phase 3 (2 phase 3 trials, 0 with posted results). 1 registered trial includes both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Oxytocin | Terlipressin | |
|---|---|---|
| Registered trials differs | 952 clinicaltrials.gov · 2026-10-03 | 118 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA label, application not recorded: GUNA-GERIATRICS openfda · 2026-10-03T17:23:44.062Z | FDA-approved: Terlivaz openfda · 2026-10-03T17:23:44.062Z |
| EU authorisation | Nothing on record ema read 2026-08-31 | Nothing on record ema read 2026-08-31 |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Oxytocin | placebo | Terlipressin | placebo |
|---|---|---|---|---|
| Abdominal pain | - | - | 21.8% | 13.4% |
| Diarrhoea | - | - | 16.4% | 5.7% |
| Nausea | - | - | 15.0% | 11.3% |
| Dyspnoea | - | - | 12.3% | 6.7% |
| Hypotension | - | - | 11.3% | 6.7% |
| Respiratory failure | - | - | 10.5% | 3.0% |
| Vomiting | - | - | 8.9% | 7.2% |
| Hypokalaemia | - | - | 8.9% | 6.2% |
| Hepatic encephalopathy | - | - | 8.5% | 11.3% |
| Fluid overload | - | - | 8.2% | 4.1% |
Trial register Oxytocin: 35 placebo-controlled trials; Terlipressin: 2. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Oxytocin side effects · Terlipressin side effects
LEGAL STATUS
Approval in each country read
| Country | Oxytocin | Terlipressin | Register |
|---|---|---|---|
| United States | FDA-approved | FDA-approved | Regulator FDA |
| European Union | Not on the register | Not on the register | Regulator EMA |
| United Kingdom | Authorised | Authorised | Regulator MHRA |
| Canada | Authorised | Not on the register | Regulator Health Canada |
| Australia | Registered | Registered | Regulator TGA |
| Switzerland | Authorised | Authorised | Regulator Swissmedic |
| Brazil | Registado | Registado | Regulator ANVISA |
| Serbia | Authorised | Authorised | Regulator ALIMS |
| Singapore | Registered | Registered | Regulator HSA |
| Turkey | Ruhsatli | Ruhsatli | Regulator TITCK |
HEAD TO HEAD
1 registered trial includes both
| NCT05806307 | Methods Decreasing Bleeding in Open Myomectomy UNKNOWN · updated 2023-04-10 |
|---|
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
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