COMPARISON
Teduglutide vs Terlipressin
5 attributes held for at least one of the two. 5 differ. Each value carries the register it came from and the date that register was read.
Answer
Teduglutide is authorised or registered in 7 and Terlipressin in 8 of the 10 registers read. Teduglutide: highest phase Phase 4 (after approval). Terlipressin: highest phase Phase 3 (2 phase 3 trials, 0 with posted results). 0 registered trials include both.
States no view on which is preferable, safer or more effective. Not medical advice.
| Teduglutide | Terlipressin | |
|---|---|---|
| Registered trials differs | 51 clinicaltrials.gov · 2026-10-03 | 118 clinicaltrials.gov · 2026-10-03 |
| FDA label differs | FDA-approved: Gattex openfda · 2026-10-03T17:23:44.062Z | FDA-approved: Terlivaz openfda · 2026-10-03T17:23:44.062Z |
| EU authorisation differs | Authorised ema · 2026-10-03 | Nothing on record ema read 2026-08-31 |
| EU authorised on differs | 2012-08-30 ema · 2026-10-03 | Not checked no record of "authorisedOn" for terlipressin |
| ATC code differs | A16AX08 ema · 2026-10-03 | Not checked no record of "atcCode" for terlipressin |
SIDE EFFECTS
Most common side effects, each beside its own placebo
| Side effect | Teduglutide | placebo | Terlipressin | placebo |
|---|---|---|---|---|
| Abdominal pain | 31.0% | 23.3% | 21.8% | 13.4% |
| Nausea | 28.6% | 18.6% | 15.0% | 11.3% |
| Vomiting | 11.9% | 9.3% | 8.9% | 7.2% |
| Gastrointestinal stoma complication | 23.8% | 7.0% | - | - |
| Abdominal distension | 21.4% | 2.3% | - | - |
| Central line systemic infections | 16.7% | 16.3% | - | - |
| Edema peripheral | 16.7% | 4.7% | - | - |
| Urinary tract infection | 14.3% | 9.3% | - | - |
| Flatulence | 11.9% | 7.0% | - | - |
| Catheter-related infection | 11.9% | 2.3% | - | - |
| Diarrhoea | - | - | 16.4% | 5.7% |
| Dyspnoea | - | - | 12.3% | 6.7% |
| Hypotension | - | - | 11.3% | 6.7% |
| Respiratory failure | - | - | 10.5% | 3.0% |
| Hypokalaemia | - | - | 8.9% | 6.2% |
| Hepatic encephalopathy | - | - | 8.5% | 11.3% |
| Fluid overload | - | - | 8.2% | 4.1% |
Trial register Teduglutide: 1 placebo-controlled trials; Terlipressin: 2. Each peptide is compared with placebo in its own trials, not with the other: a dash means the event is not in that peptide's top list. Teduglutide side effects · Terlipressin side effects
LEGAL STATUS
Approval in each country read
| Country | Teduglutide | Terlipressin | Register |
|---|---|---|---|
| United States | FDA-approved | FDA-approved | Regulator FDA |
| European Union | Authorised | Not on the register | Regulator EMA |
| United Kingdom | Authorised | Authorised | Regulator MHRA |
| Canada | Authorised | Not on the register | Regulator Health Canada |
| Australia | Registered | Registered | Regulator TGA |
| Switzerland | Authorised | Authorised | Regulator Swissmedic |
| Brazil | Registado | Registado | Regulator ANVISA |
| Serbia | Not on the register | Authorised | Regulator ALIMS |
| Singapore | Not on the register | Registered | Regulator HSA |
| Turkey | Not on the register | Ruhsatli | Regulator TITCK |
Values reproduce public registers on the dates shown. This comparison states no view on which compound is preferable, safer or more effective. Not medical, legal or regulatory advice.
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