octapeptide hormone

Angiotensin II

US: FDA-approvedEU: AuthorisedUK: AuthorisedCA: Not on the registerAU: Status unknownCH: Not on the registerBR: Not on the registerRS: Not on the registerSG: Not on the registerTR: Not on the register

Answer

Angiotensin II is authorised or registered in the US, the EU and the UK: 3 of the 10 registers read. Highest trial phase: Phase 4 (after approval). It has 364 registered trials, 61 of them running. Brand names on the FDA label register: Angiotensin Ii and Giapreza.

RegulatorTrial register10 regulators' registers, read 2026-09-03 to 2026-10-03 · ClinicalTrials.gov and EU CTIS, read 2026-10-03

Not medical, legal or regulatory advice.

Registered trials364Trial register ClinicalTrials.gov and EU CTIS
Running now61Trial register recruiting, active or enrolling
Results posted15Trial register with results on the register
Stopped early11.5%Trial register all peptides: 10%

364 trials by status

Trial register
Running 61Completed 194Stopped early 42Status unknown 56Other or not stated 11

ClinicalTrials.gov and EU CTIS · read 2026-10-03 · 15 trials have posted results

Trials first submitted per year

Trial register

ClinicalTrials.gov first-submitted date, last 10 years · read 2026-10-03. 2026 is not complete. 194 trials carry no first-submitted date (EU CTIS publishes none, or the year is outside this range).

Status by jurisdiction

World map
Authorised or registeredNot on the register, or withdrawnNot read yet, or status unknown
WhereStatusRegisterRead
United StatesFDA-approvedFDA, openfda2026-10-03
European UnionAuthorisedEMA, ema2026-10-03
United KingdomAuthorisedMHRA, uk-mhra2026-10-03
CanadaNot on the registerHealth Canada, ca-dpd2026-09-03
AustraliaStatus unknownTGA, au-artgnot read
SwitzerlandNot on the registerSwissmedic, ch-swissmedic2026-09-03
BrazilNot on the registerANVISA, br-anvisa2026-09-03
SerbiaNot on the registerALIMS, rs-alims2026-09-03
SingaporeNot on the registerHSA, sg-hsa2026-09-03
TurkeyNot on the registerTITCK, tr-titck2026-09-03

An EU decision applies in the 30 territories the EU register covers: its member states, and Iceland, Liechtenstein and Norway. A dashed tile has no register read for this peptide.

Side effects

Trial register
1 placebo-controlled trial · 163 people on Angiotensin II · grey is placebo
Multi-organ failure15.3% 14.6%
Septic shock11% 6.3%
Atrial fibrillation10.4% 10.1%
Thrombocytopenia9.2% 6.3%
Hypokalaemia8% 6.3%
ClinicalTrials.gov posted results · read 2026-10-03All side effects

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REGISTERED TRIALS

Newest 10 of 364 trials

All 364 trials
NCT06746753
Mechanistic Assessment of Norepinephrine Therapy vs. Angiotensin-II in Septic Shock
not yet recruiting participants · register updated 2026-09-24
NCT06539234
Angiotensin II Stress Test. Renin Kinetics During Treatment of Vasoplegic Shock With Angiotensin II.
currently recruiting participants · register updated 2026-09-16
NCT06693726
Early Angiotensin II in the Emergency Department
currently recruiting participants · register updated 2026-09-02
NCT07775846
QUARTET-DKD: Quadruple Therapy for Type 2 Diabetic Nephropathy
not yet recruiting participants · register updated 2026-08-20
NCT04715568
Secondhand Tobacco Smoke and Cardiovascular Disease
currently recruiting participants · register updated 2026-08-19
NCT07181109
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Ris
currently recruiting participants · register updated 2026-08-19
NCT06588686
A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic Pulmonary Fibrosis.
running, but no longer enrolling · register updated 2026-08-17
2025-524783-38-00
Spironolactone and SGLT2 inhibitor to Address Fontan circulatory failure and Enhance Resilience: The SAFER-Fontan trial
no status recorded · register updated 2026-08-14
2023-504597-37-00
A pivotal Phase 3, multicenter, randomized, double-blind, placebo-controlled study of the efficacy and safety of DMX-200 in patien
no status recorded · register updated 2026-08-12
NCT06150560
A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)
enrolling by invitation only · register updated 2026-08-11

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