amylin analogue
Cagrilintide clinical trials
Answer
Cagrilintide has 66 registered trials: 17 running, 24 completed, 2 stopped early. 1 posted results.
Trial registerClinicalTrials.gov and EU CTIS, read 2026-10-03
| Trial | Title | Status | Phase | Registered | Results |
|---|---|---|---|---|---|
| 2025-524249-29-00 Trial register | A placebo-controlled comparability study to compare two presentations of cagrilintide for weight management in participants with overweight or obesity | Not stated | 3 | - | - |
| NCT05567796 Trial register | A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight | running, but no longer enrolling | - | 2022-10-05 | - |
| NCT06323174 Trial register | A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise | completed | - | 2024-03-21 | - |
| NCT07011667 Trial register | A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term | running, but no longer enrolling | - | 2025-06-09 | - |
| NCT07253285 Trial register | A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight | currently recruiting participants | - | 2025-11-28 | - |
| NCT07564414 Trial register | A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Los | currently recruiting participants | - | 2026-05-04 | - |
| NCT06131372 Trial register | A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema | completed | - | 2023-11-14 | - |
| 2025-521384-12-00 Trial register | A research study to compare blood levels of cagrilintide after multiple doses of different versions of cagrilintide in adults with overweight or obesity | Not stated | 1 | - | - |
| NCT06797869 Trial register | A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy | completed | - | 2025-01-29 | - |
| NCT07010432 Trial register | The Role of the Amylin Analogue Cagrilintide in Bone Metabolism | currently recruiting participants | - | 2025-06-08 | - |
| NCT07184086 Trial register | A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet | running, but no longer enrolling | - | 2025-09-19 | - |
| NCT06323161 Trial register | A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal I | completed | - | 2024-03-21 | - |
| NCT06534411 Trial register | A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGL | completed | 3 | 2024-08-02 | - |
| NCT07282613 Trial register | A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes | currently recruiting participants | - | 2025-12-15 | - |
| 2023-506924-94-00 Trial register | The cardiovascular safety and efficacy of cagrilintide 2.4 mg s.c. in combination with semaglutide 2.4 mg s.c. (CagriSema 2.4 mg/2.4 mg s.c.) once-weekly in par | Not stated | 3 | - | - |
| 2023-509176-42-00 Trial register | Efficacy, safety and pharmacokinetics of cagrilintide s.c. 2.4 mg as monotherapy and in combination with semaglutide s.c. 2.4 mg (CagriSema) once weekly for wei | Not stated | 3 | - | - |
| 2024-519530-24-00 Trial register | Efficacy and safety of cagrilintide for weight management in participants with overweight or obesity | Not stated | 3 | - | - |
| NCT06221969 Trial register | A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With | completed | 3 | 2024-01-24 | - |
| NCT07220759 Trial register | Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With Cagrilintide | running, but no longer enrolling | - | 2025-10-24 | - |
| NCT07605052 Trial register | A Research Study to Compare Blood Levels of Two Different Versions of Cagrilintide in Adults With Excess Body Weight | completed | - | 2026-05-22 | - |
| NCT07745504 Trial register | A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight | currently recruiting participants | - | 2026-08-04 | - |
| NCT05669755 Trial register | REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels | running, but no longer enrolling | - | 2023-01-03 | - |
| NCT06716307 Trial register | A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overwei | completed | - | 2024-12-04 | - |
| 2025-524206-15-00 Trial register | A research study looking into how cagrilintide influences food intake and appetite in people with overweight or obesity | Not stated | 1 | - | - |
| NCT06719011 Trial register | A Study on How NNC0174-1213 Works in People With Overweight or Obesity. | completed | - | 2024-12-05 | - |
| 2024-519531-41-00 Trial register | Efficacy and safety of cagrilintide for weight management in participants with overweight or obesity and type 2 diabetes | Not stated | 3 | - | - |
| NCT07220642 Trial register | Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide | running, but no longer enrolling | - | 2025-10-24 | - |
| 2025-522488-14-00 Trial register | A clinical study to compare efficacy and safety of two different doses of CagriSema and semaglutide in participants with obesity with or without type 2 diabetes | Not stated | 3 | - | - |
| 2023-509600-15-00 Trial register | Efficacy and safety of co-administered cagrilintide and semaglutide (CagriSema) 1.0 mg/1.0 mg s.c. once weekly versus tirzepatide 5 mg s.c. once weekly in parti | Not stated | 3 | - | - |
| 2023-509662-38-00 Trial register | Efficacy and safety of co-administered cagrilintide and semaglutide (CagriSema) once weekly versus placebo in participants with type 2 diabetes and painful diab | Not stated | 2 | - | - |
| 2024-517883-49-00 Trial register | The Role of the Amylin Analogue Cagrilintide in Bone Metabolism | Not stated | 1 | - | - |
| NCT07357740 Trial register | A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 Diabetes | withdrawn before enrolling anyone | - | 2026-01-21 | - |
| NCT07357766 Trial register | A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body Weight | withdrawn before enrolling anyone | - | 2026-01-21 | - |
| 2023-506929-11-00 Trial register | Efficacy and safety of cagrilintide s.c. in combination with semaglutide s.c. (CagriSema s.c.) once-weekly in participants with overweight or obesity | Not stated | 3 | - | - |
| NCT06065540 Trial register | A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes T | completed | - | 2023-10-04 | - |
| NCT07597018 Trial register | A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or Obesity | currently recruiting participants | - | 2026-05-19 | - |
| NCT07607587 Trial register | Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events | currently recruiting participants | - | 2026-05-26 | - |
| NCT06289504 Trial register | A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body Weight | completed | - | 2024-03-04 | - |
| NCT07557953 Trial register | A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or Obesity | currently recruiting participants | - | 2026-04-30 | - |
| NCT07527195 Trial register | Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health) | currently recruiting participants | - | 2026-04-14 | - |
| 2024-512144-39-00 Trial register | Long-term efficacy and safety of cagrilintide s.c. 2.4 mg in combination with semaglutide s.c. 2.4 mg (CagriSema 2.4 mg/2.4 mg) once weekly versus placebo in pa | Not stated | 3 | - | - |
| NCT06388187 Trial register | A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight | completed | - | 2024-04-29 | - |
| NCT07411560 Trial register | A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or Obese | currently recruiting participants | - | 2026-02-17 | - |
| NCT06409130 Trial register | Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease | completed | - | 2024-05-10 | - |
| 2025-522920-28-00 Trial register | Understanding the effect of CagriSema, cagrilintide, and semaglutide on muscle health | Not stated | 1 | - | - |
| 2023-509273-24-00 Trial register | Efficacy and safety of cagrilintide s.c. in combination with semaglutide s.c. (CagriSema s.c. 1.0 mg/1.0 mg and 1.7 mg/1.7 mg) once-weekly in participants with | Not stated | 3 | - | - |
| NCT06403761 Trial register | Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 Diabetes | completed | - | 2024-05-08 | - |
| NCT06131437 Trial register | A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight | completed | 3 | 2023-11-14 | - |
| 2023-509483-20-00 Trial register | Investigating how CagriSema, semaglutide and cagrilintide regulate insulin effects in the body of people with type 2 diabetes. | Not stated | 1 | - | - |
| 2022-502677-42-00 Trial register | Efficacy and safety of co-administered cagrilintide and semaglutide (CagriSema) s.c. in doses 2.4 mg/2.4 mg and 1.0 mg/1.0 mg once weekly versus placebo in part | Not stated | 3 | - | - |
| 2022-502678-18-00 Trial register | Efficacy and safety of co-administered cagrilintide and semaglutide (CagriSema) s.c. in doses 2.4/2.4 mg and 1.0/1.0 mg once weekly versus semaglutide 2.4 mg an | Not stated | 3 | - | - |
| NCT05394519 Trial register | A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose Weight | completed | - | 2022-05-27 | - |
| 2022-502679-43-00 Trial register | Efficacy and safety of co-administered cagrilintide and semaglutide (CagriSema) s.c. in doses 2.4 mg/2.4 mg and 1.0 mg/1.0 mg once weekly versus placebo in part | Not stated | 3 | - | - |
| NCT05813925 Trial register | A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose Weight | completed | - | 2023-04-14 | - |
| NCT06780449 Trial register | A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity | running, but no longer enrolling | - | 2025-01-17 | - |
| 2023-505857-42-00 Trial register | Efficacy and safety of co-administered cagrilintide and semaglutide (CagriSema 2.4 mg/2.4 mg) once weekly versus semaglutide 2.4 mg, cagrilintide 2.4 mg and pla | Not stated | 2 | - | - |
| NCT05996848 Trial register | A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose Weight | completed | - | 2023-08-18 | - |
| NCT06207877 Trial register | A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body Weight | completed | - | 2024-01-17 | - |
| NCT06267092 Trial register | A Study of How CagriSema Works on Appetite in People With Excess Body Weight | completed | - | 2024-02-20 | - |
| NCT04982575 Trial register | Research Study to Look at How Well Cagrilintide Together With Semaglutide Works in People With Type 2 Diabetes | completed | - | 2021-07-29 | Posted |
| 2023-508170-28-00 Trial register | Effects of NNC0194-0499 alone and in combination with semaglutide, of semaglutide alone, and of cagrilintide alone and in combination with semaglutide on liver | Not stated | 2 | - | - |
| NCT04940078 Trial register | A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Combined Versus Separate Injections in People With Overweight or Obesity | completed | - | 2021-06-25 | - |
| NCT05564104 Trial register | A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With No | completed | - | 2022-10-03 | - |
| 2023-506931-13-00 Trial register | Efficacy and safety of cagrilintide s.c. in combination with semaglutide s.c. (CagriSema s.c.) once-weekly in participants with overweight or obesity and type 2 | Not stated | 3 | - | - |
| 2023-506961-74-00 Trial register | Efficacy and safety investigation of NNC0194-0499 co-administered with semaglutide in subjects with non-alcoholic steatohepatitis: a dose-ranging, placebo-contr | Not stated | 2 | - | - |
| NCT05804162 Trial register | A Research Study Looking at How Cagrilintide Works on the Heart Rhythm in Healthy Participants | completed | - | 2023-04-07 | - |
Source: ClinicalTrials.gov and EU CTIS, read 2026-10-03. Not medical advice.
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