epoxyketone tetrapeptide
Carfilzomib dose
Answer
FDA label for KYPROLIS: The recommended starting dosage of Kyprolis is 20 mg/m 2 on Cycle 1, Day 1. Trials with posted results tested 5 doses, most often 70 mg, 27 mg, 20 mg.
Not dosing advice.
FDA LABEL
What the approved labels state
KYPROLIS NDA202714 · label of 2025-06-18 Regulator
The recommended starting dosage of Kyprolis is 20 mg/m 2 on Cycle 1, Day 1.
IN TRIALS
Doses tested in 91 trials with posted results
| Dose in the arm title | Trials | People on it | Phases |
|---|---|---|---|
| 70 mg | 3 | 361 | 1/2/3 |
| 27 mg | 2 | 305 | 2/3 |
| 20 mg | 1 | 94 | 2 |
| 36 mg | 1 | 41 | 1/2 |
| 56 mg | 1 | 33 | 1 |
Trial register Read from the titles of arms that received Carfilzomib (n ≥ 20). An arm naming several doses counts under each; a schedule or escalation is on the trial record. All trials.
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