somatostatin analogue
Lanreotide clinical trials
Answer
Lanreotide has 125 registered trials: 10 running, 72 completed, 21 stopped early. 34 posted results.
Trial registerClinicalTrials.gov and EU CTIS, read 2026-10-03
| Trial | Title | Status | Phase | Registered | Results |
|---|---|---|---|---|---|
| 2024-516616-24-00 Trial register | A Phase 3 randomized 3-arm trial (double-blind Debio 4126, placebo control, and open-label Debio 4126), to assess the efficacy and safety of Debio 4126, a 12-we | Not stated | 3 | - | - |
| NCT06878664 Trial register | Randomized Interval Assessment Trial of Lu177-Dotatate in Slowly Progressive G1-2 Advanced Midgut Neuroendocrine Tumors | currently recruiting participants | - | 2025-03-17 | - |
| 2023-509334-19-00 Trial register | Trial title: Phase 1b/3 global, randomized, controlled, open-label trial comparing treatment with RYZ101 to standard of care (SoC) therapy in subjects with inop | Not stated | 3 | - | - |
| 2023-508723-12-00 Trial register | A randomized, multi-center, open-label, active-controlled Phase 3 trial to assess the efficacy and safety of octreotide subcutaneous depot (CAM2029) versus octr | Not stated | 3 | - | - |
| NCT07087054 Trial register | Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen | currently recruiting participants | - | 2025-07-09 | - |
| NCT05050942 Trial register | A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With GEP-NET | running, but no longer enrolling | - | 2021-09-21 | - |
| 2023-505884-35-00 Trial register | Absorbed Tumor Dose in Peptide Receptor Radionuclide Therapy with long-acting Somatostatin Analogues - ATSA trial | Not stated | 4 | - | - |
| NCT07534371 Trial register | Analysis of Optimal Treatment Sequencing of Surufatinib and Somatostatin Analogs in Neuroendocrine Tumors: A Retrospective Cohort Study | running, but no longer enrolling | - | 2026-04-08 | - |
| NCT05048901 Trial register | Cabozantinib and Lanreotide as Treatment for Gastroenteropancreatic Neuroendocrine Tumors | currently recruiting participants | - | 2021-09-17 | - |
| NCT02127437 Trial register | Lanreotide In Polycystic Kidney Disease Study | completed | - | 2014-04-30 | - |
| NCT06807437 Trial register | Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula | currently recruiting participants | - | 2025-02-04 | - |
| NCT05477576 Trial register | Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy | currently recruiting participants | - | 2022-07-28 | - |
| NCT05361668 Trial register | Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome | completed | - | 2022-04-27 | Posted |
| NCT03946527 Trial register | LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA) | running, but no longer enrolling | - | 2019-05-10 | - |
| 2025-521243-20-00 Trial register | A Phase 2, Randomized, Double-blinded, Placebo-controlled, Dose Range-finding, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ALXN2 | Not stated | 2 | - | - |
| NCT05364944 Trial register | A Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Debio 4126 in Participants With Acromegaly or Functioning Gastroenteropanc | terminated before completion | - | 2022-05-04 | - |
| 2022-502703-30-00 Trial register | Continuing Somatostatin Analogues Upon progression in Neuroendocrine tumour pAtients (SAUNA trial) | Not stated | 4 | - | - |
| NCT03289741 Trial register | A Study to Evaluate Patient Experience in the Therapy of Neuroendocrine Tumors Treated With Octreotide Long Acting Release Versus Lanreotide | completed | - | 2017-09-21 | Posted |
| NCT03792555 Trial register | A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Evolve) | completed | - | 2018-12-27 | Posted |
| NCT00353496 Trial register | Study of Lanreotide Autogel in Non-functioning Entero-pancreatic Endocrine Tumours | completed | - | 2006-07-18 | Posted |
| NCT02795858 Trial register | A Phase II Study of Ramucirumab With Somatostatin Analog Therapy in Patients With Advanced, Progressive Carcinoid Tumors | completed | - | 2016-06-07 | Posted |
| NCT05431803 Trial register | Real-World Study (RWS) of Lanreotide Autogel (LAN) for the Treatment of Patients With Acromegaly in China | completed | - | 2022-06-24 | - |
| NCT04696042 Trial register | Asian Investigation of Lanreotide Autogel® in the Management of GEP-NETs | completed | - | 2021-01-06 | - |
| NCT02736448 Trial register | 177Lutethium - Peptide Receptor Radionuclide Therapy (Lu-PRRT) Plus Capecitabine Versus Lu-PRRT in FDG Positive, Gastro-entero-pancreatic Neuroendocrine Tumors | terminated before completion | - | 2016-04-07 | - |
| NCT04649580 Trial register | United Kingdom (UK) Patient Preference Study of Somatuline Autogel and Treatment Administration Setting | completed | - | 2020-09-23 | - |
| 2024-516612-16-00 Trial register | A Phase II trial aiming to assess the safety and activity of the combination of cabozantinib plus lanreotide in gastroenteropancreatic (GEP) and thoracic neuroe | Not stated | 2 | - | - |
| NCT04852679 Trial register | Study to Assess the Efficacy and Safety of Lanreotide Autogel® in Chinese Participants With GEP-NETs | completed | - | 2021-04-21 | Posted |
| NCT06607666 Trial register | Acromegaly Resistant to Conventional Dose of First Generation Somatostatin Ligands | completed | - | 2024-09-23 | - |
| NCT05701241 Trial register | Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtients | currently recruiting participants | - | 2023-01-05 | - |
| 2024-513200-34-00 Trial register | Safety of Lanreotide 120 mg ATG in combination with Metformin in patients with progressive advanced Well-differentiated gastro-intestinal (GI) or lung carcinoid | Not stated | 2 | - | - |
| NCT01070758 Trial register | Lanreotide Autogel Treatment of Patients With Congenital Hyperinsulinism of Infancy | completed | - | 2010-02-18 | - |
| NCT05922579 Trial register | A Study to Collect the Somatuline® Injector Device Preferences of Patients Living With Neuroendocrine Tumor (NET) and Nurses Involved in the Care of Patients Wi | terminated before completion | - | 2023-06-19 | - |
| NCT02859064 Trial register | Study of Lanreotide in Patients With Metastatic Gastrointestinal Neuroendocrine Tumors Who Are Undergoing Liver-directed Radioembolization With Yttrium-90 Micro | terminated before completion | - | 2016-08-08 | Posted |
| NCT03043664 Trial register | Study of Pembrolizumab With Lanreotide Depot for Gastroenteropancreatic Neuroendocrine Tumors | completed | - | 2017-02-06 | Posted |
| NCT03967249 Trial register | Extension Study of IONIS-GHR-LRx Administered to Participants With Acromegaly Being Treated With Long-acting Somatostatin Receptor Ligands | completed | - | 2019-05-23 | - |
| NCT01923649 Trial register | SOMATULINE Autogel 90 mg IN DUMPING SYNDROME | completed | - | 2013-08-15 | - |
| NCT02288377 Trial register | A Study Evaluating Lanreotide as Maintenance Therapy in Patients With Non-Resectable Duodeno-Pancreatic Neuroendocrine Tumors (REMINET) | terminated before completion | - | 2014-11-11 | Posted |
| NCT01538966 Trial register | Acromegaly Combination Treatment Study | terminated before completion | - | 2012-02-27 | Posted |
| NCT00690898 Trial register | Lanreotide as Primary Treatment for Acromegalic Patients With Pituitary Gland Macroadenoma | completed | - | 2008-06-05 | Posted |
| NCT00774930 Trial register | An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome | completed | - | 2008-10-17 | Posted |
| NCT00842348 Trial register | Study of Lanreotide Autogel 120 mg in Patients With Non-functioning Entero- Pancreatic Endocrine Tumour | completed | - | 2009-02-12 | Posted |
| NCT02651987 Trial register | Efficacy and Safety Study in Pancreatic or Midgut Neuroendocrine Tumours Having Progressed Radiologically While Previously Treated With Lanreotide Autogel® 120 | completed | - | 2016-01-11 | Posted |
| NCT00383708 Trial register | Lanreotide Autogel and Pegvisomant Combination Therapy in Acromegalic Patients | completed | - | 2006-10-03 | Posted |
| NCT02683941 Trial register | Efficacy and Safety of Lanreotide Autogel/ Depot 120 mg vs. Placebo in Subjects With Lung Neuroendocrine Tumours | terminated before completion | - | 2016-02-17 | Posted |
| NCT03174353 Trial register | A Phase II Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula | completed | - | 2017-06-02 | Posted |
| NCT02685709 Trial register | Comparison of Oral Octreotide Capsules to Injectable Somatostatin Analogs in Acromegaly | completed | - | 2016-02-19 | Posted |
| NCT03158090 Trial register | The Longitudinal Approach to Acromegaly: A Pattern of Treatment and Comparative Effectiveness Research | currently recruiting participants | - | 2017-05-06 | - |
| NCT01861717 Trial register | A Pilot Study of Pre- and Post-operative Use of Somatuline Depot. | terminated before completion | - | 2013-05-24 | Posted |
| NCT04427787 Trial register | A Trial Aiming to Assess the Safety and Activity of the Combination of Cabozantinib Plus Lanreotide in GEP and NET | last verified some time ago; the register no longer confirms its status | - | 2020-06-11 | - |
| NCT03947762 Trial register | Lanreotide 120mg Effectiveness in Subjects With Pancreatic Neuroendocrine Tumours (PanNET) in Routine Clinical Practice. | terminated before completion | - | 2019-05-13 | - |
| NCT02823691 Trial register | The MetNET-2 Trial | last verified some time ago; the register no longer confirms its status | - | 2016-07-06 | - |
| NCT02973204 Trial register | Circulating Tumor Cells and Tumor DNA in HCC and NET | completed | - | 2016-11-25 | - |
| NCT03012594 Trial register | Lanreotide in the Treatment of Small Bowel Motility Disorders | completed | - | 2017-01-06 | Posted |
| NCT00447499 Trial register | Assessment of the Ability of Subjects With Acromegaly or Their Partners to Administer Somatuline Autogel | completed | - | 2007-03-14 | Posted |
| NCT00216372 Trial register | Efficacy and Safety of Lanreotide Microparticles as Palliative Treatment in Peritoneal Carcinomatosis | completed | - | 2005-09-22 | - |
| NCT00326469 Trial register | Efficacy and Safety of Lanreotide Autogel in Tumour Stabilization of Patients With Progressive Neuroendocrine Tumours | completed | - | 2006-05-16 | - |
| NCT01234168 Trial register | A Study to Assess Neuroendocrine Tumour (NET) Patients Currently Treated by Somatuline Autogel for History of Carcinoid Syndrome Associated With Episodes of Dia | completed | - | 2010-10-20 | - |
| NCT03895463 Trial register | Study to Assess the Use of Lanreotide Autogel® 120 mg in Patients With Locally Advanced or Metastatic Gastroenteropancreatic Neuroendocrine Tumours (GEP-NETs) i | withdrawn before enrolling anyone | - | 2019-03-29 | - |
| NCT02698410 Trial register | Efficacy and Safety of Lanreotide Autogel (ATG) in Combination With Temozolomide in Subjects With Thoracic Neuroendocrine Tumors. | completed | - | 2016-03-03 | Posted |
| NCT04557137 Trial register | Fatigue and Quality of Life in Patients With Neuroendocrine Neoplasia | last verified some time ago; the register no longer confirms its status | - | 2020-09-14 | - |
| NCT03562091 Trial register | Perception of Information and Quality of Life in Neuroendocrine Tumour on Lanreotide Autogel | completed | - | 2018-06-19 | - |
| NCT02730104 Trial register | Community-based Neuroendocrine Tumor (NET) Research Study | completed | - | 2016-04-01 | - |
| NCT00288522 Trial register | Lanreotide (Somatuline Autogel) in Thyroid-associated Ophthalmopathy Treatment | terminated before completion | - | 2006-02-08 | - |
| NCT03112694 Trial register | Switching From Octreotide to Lanreotide - A Look Back at Patients With Neuroendocrine Tumors | completed | - | 2017-04-13 | - |
| NCT04003519 Trial register | Study to Predict Lanreotide-induced Disease Activity Normalization in Acromegaly | withdrawn before enrolling anyone | - | 2019-07-01 | - |
| NCT00092287 Trial register | Comparison of Lanreotide Autogel® and Sandostatin LAR Depot in the Treatment of Clinical Symptoms Associated With Carcinoid Syndrome | terminated before completion | - | 2004-09-27 | - |
| NCT00210457 Trial register | Efficacy and Safety of Lanreotide Autogel (60, 90 or 120 mg) in Acromegalic Patients | completed | - | 2005-09-21 | - |
| NCT04065165 Trial register | Lanreotide Combined With Telotristat Ethyl or Placebo for the First-line Treatment in Patients With Advanced Well Differentiated Small Intestinal Neuroendocrine | withdrawn before enrolling anyone | - | 2019-08-22 | - |
| NCT04198402 Trial register | Microbiotic Analysis in Digestive Endocrine Tumors | last verified some time ago; the register no longer confirms its status | - | 2019-12-04 | - |
| NCT00444873 Trial register | Effect of 120mg Somatuline Autogel at Different Dose Intervals (28, 42 or 56 Days) in Patients With Acromegaly | completed | - | 2007-03-08 | - |
| NCT00681187 Trial register | Somatuline Autogel Preference and Health Economy Study | completed | - | 2008-05-21 | Posted |
| NCT01313273 Trial register | Study of Lanreotide in Non Metastatic Castration-resistant Prostate Cancer Patients | terminated before completion | - | 2011-03-11 | Posted |
| NCT02365584 Trial register | Quality of Life in Patients With Inoperable Malignant Bowel Obstruction | terminated before completion | - | 2015-02-19 | Posted |
| NCT00216398 Trial register | Lanreotide Autogel in Patients With Acromegaly Previously Treated With Octreotide LAR | completed | - | 2005-09-22 | - |
| NCT00149188 Trial register | Somatuline Autogel: Acromegaly Self/Partner Injection Study | completed | - | 2005-09-08 | - |
| NCT00517491 Trial register | Study to Evaluate Patients With Acromegaly Treated With Lanreotide Autogel (Somatuline ATG) | withdrawn before enrolling anyone | - | 2007-08-17 | - |
| NCT02807233 Trial register | Lanreotide Autogel 120 mg at Extended Dosing Intervals (>4 Weeks) in Acromegalic Subjects | completed | - | 2016-06-21 | - |
| NCT00234520 Trial register | A Study to Evaluate the Risk of Developing a Heart Condition Called Valvular Regurgitation in Patients With Acromegaly Treated With Either Lanreotide or Octreot | completed | - | 2005-10-07 | - |
| NCT00234572 Trial register | Efficacy and Safety Study of Varying Doses of Lanreotide Autogel in Patients With Acromegaly | completed | - | 2005-10-07 | - |
| NCT02075606 Trial register | Circulating Tumour Cells in Somatuline Autogel Treated NeuroEndocrine Tumours Patients | completed | - | 2014-03-03 | Posted |
| NCT03083210 Trial register | Study of Lanreotide in Metastatic or Recurrent Grade I-II Hindgut NET | last verified some time ago; the register no longer confirms its status | - | 2017-03-17 | - |
| NCT02231762 Trial register | Combination of Lanreotide Autogel 120mg and Temozolomide in Progressive GEP-NET | completed | - | 2014-09-04 | Posted |
| NCT02396953 Trial register | Study to Determine the Maximum Tolerated Dose, Safety and Tolerability of a Single Dose of Lanreotide Prolonged Release Formulation (PRF) in Subjects With Acrom | completed | - | 2015-03-24 | Posted |
| NCT02275338 Trial register | Study to Assess Efficacy and Safety of Lanreotide Autogel 120 MG in Treatment of Clinical Symptoms Associated With Inoperable Malignant Intestinal Obstruction | completed | - | 2014-10-27 | Posted |
| NCT00729313 Trial register | Efficacy and Safety of Lanreotide Versus Placebo for Treatment of Patients With Digestive Fistulae | completed | - | 2008-08-07 | - |
| NCT00701363 Trial register | Study to Assess the Efficacy of an Extended Injection Interval Schedule of Lanreotide Autogel in Acromegalic Subjects | completed | - | 2008-06-19 | Posted |
| NCT02493517 Trial register | Efficacy and Safety of Lanreotide Autogel® 60, 90 or 120 mg With Lanreotide 40 mg Prolonged Release (PR) in Acromegaly | completed | - | 2015-07-09 | Posted |
| NCT00499993 Trial register | Efficacy and Tolerability of Lanreotide (Autogel 120 mg) in Patients With Acromegaly | completed | - | 2007-07-12 | - |
| NCT00891371 Trial register | Lanreotide Autogel in the Symptomatic Treatment of Refractory Diarrhea | completed | - | 2009-05-01 | Posted |
| NCT01840449 Trial register | Somatuline Predictive Factors in Acromegaly and NET | completed | - | 2013-04-23 | - |
| NCT02020499 Trial register | Predictive Factors Study | terminated before completion | - | 2013-12-25 | - |
| NCT00686348 Trial register | Somatuline® Depot (Lanreotide) for Acromegaly Post-Marketing Observational Study | completed | - | 2008-05-29 | - |
| NCT01471405 Trial register | One Year Follow-up of Study 2-79-52030-207 (PRIMARYS) in Acromegalic Patients With Macroadenoma | completed | - | 2011-11-10 | - |
| NCT00747500 Trial register | Non Interventional Post Marketing Programme in Acromegaly | completed | - | 2008-09-04 | - |
| NCT00747786 Trial register | Non Interventional Post Marketing Programme in Neuroendocrine Tumours | completed | - | 2008-09-04 | - |
| NCT01333384 Trial register | Study in Polish Acromegalic Patients Treated With Somatuline Autogel | completed | - | 2011-04-08 | - |
| NCT02396966 Trial register | Quality of Life (QoL) in Subjects With Acromegaly Under Lanreotide Autogel® Treatment. | completed | - | 2015-03-24 | - |
| NCT02698384 Trial register | Therapeutic Strategies in Acromegalic Subjects Treated With Lanreotide 120mg | terminated before completion | - | 2016-03-03 | - |
| NCT02788578 Trial register | A Retrospective Data Analysis of Therapy With PRRT Combined With Lanreotide Autogel® for Neuroendocrine Tumours | terminated before completion | - | 2016-06-02 | - |
| NCT03017690 Trial register | Lanreotide and Octreotide Long Acting Release (LAR) for Patients With Advanced Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) | completed | - | 2017-01-11 | - |
| NCT01137682 Trial register | Efficacy and Safety of Pasireotide Long Acting Release (LAR) Versus Octreotide LAR or Lanreotide Autogel (ATG) in Patients With Inadequately Controlled Acromega | completed | - | 2010-06-04 | Posted |
| NCT02354768 Trial register | Evaluation of Lanreotide Efficacity in High Output Stoma: a Multicentric Randomized Study | terminated before completion | - | 2015-02-03 | - |
| NCT03439709 Trial register | Multicenter Evaluation of the Effect of Upfront Radiosurgery on Residual Growth Hormone-secreting Pituitary Adenoma | last verified some time ago; the register no longer confirms its status | - | 2018-02-20 | - |
| NCT01677910 Trial register | TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome) | completed | - | 2012-08-30 | Posted |
| NCT02351128 Trial register | Treatment of Unresecable and/or Metastatic Merkel Cell Carcinoma by Somatostatine Analogues | completed | - | 2015-01-30 | - |
| NCT01616927 Trial register | Study of Lanreotide to Treat Polycystic Kidney Disease | last verified some time ago; the register no longer confirms its status | - | 2012-06-12 | - |
| NCT01731925 Trial register | A Study of Sunitinib Versus Placebo in Combination With Lanreotide in Patients With Progressive Advanced/Metastatic Midgut Carcinoid Tumors | last verified some time ago; the register no longer confirms its status | - | 2012-11-22 | - |
| NCT01372007 Trial register | Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcarcinoma | completed | - | 2011-06-13 | - |
| NCT02668172 Trial register | Pasireotide LAR and Pegvisomant Study in Acromegaly | last verified some time ago; the register no longer confirms its status | - | 2015-12-07 | - |
| NCT01076803 Trial register | Efficacy and Safety of Lanreotide 120 Milligram (mg) as a Palliative Treatment of Clinical Symptoms Associated With Malignant Intestinal Obstruction in Inoperab | completed | - | 2010-02-26 | - |
| NCT01354405 Trial register | Somatostatin Analogues as a Volume Reducing Treatment of Polycystic Livers (RESOLVE) | completed | - | 2011-05-16 | - |
| NCT01315795 Trial register | Lanreotide Autogel in the Treatment of Symptomatic Polycystic Liver Disease | completed | - | 2011-03-15 | - |
| NCT02054637 Trial register | Resolving Bile Reflux by Lanreotide in Patients With Roux-en-Y Gastrojejunostomy | last verified some time ago; the register no longer confirms its status | - | 2014-02-04 | - |
| NCT00652379 Trial register | Co-treatment With Pegvisomant and a Somatostatin Analogue (SA) in SA-responsive Acromegalic Patients | completed | - | 2008-04-03 | - |
| NCT00630695 Trial register | Prevention of Lymphorrhea by Lanreotide in Axillary Dissection for Breast Cancer | completed | - | 2008-03-07 | - |
| NCT00993356 Trial register | Preoperative Lanreotide Treatment in Acromegalic Patients With Macroadenomas | last verified some time ago; the register no longer confirms its status | - | 2009-10-12 | - |
| NCT00495846 Trial register | GH, IGF-I and Somatostatin Analogues in Hepatocellular Carcinoma | completed | - | 2007-07-03 | - |
| NCT00916916 Trial register | Lanreotide Levels in Acromegaly | last verified some time ago; the register no longer confirms its status | - | 2009-06-10 | - |
| NCT00565097 Trial register | Lanreotide as Treatment of Polycystic Livers | completed | - | 2007-11-29 | - |
| NCT00771888 Trial register | Open-Label Extension of LOCKCYST Trial | last verified some time ago; the register no longer confirms its status | - | 2008-10-15 | - |
| NCT00703079 Trial register | Impact of Somatostatin Analogs vs. Surgery on Glucose Metabolism in Acromegaly | completed | - | 2008-06-23 | - |
| NCT00627796 Trial register | Lanreotide Autogel-120 mg as First-Line Treatment of Acromegaly | completed | - | 2008-03-03 | - |
| NCT00615004 Trial register | Cardiovascular Outcome After Surgery or Somatostatin Analogues | completed | - | 2008-02-01 | - |
| NCT00543179 Trial register | Treatment of the Dumping Syndrome With Lanreotide Autogel® | last verified some time ago; the register no longer confirms its status | - | 2007-10-12 | - |
| NCT00145405 Trial register | Comparable Effects of Lanreotide Autogel and Octreotide LAR on GH, IGF-I Levels and Patient Satisfaction | completed | - | 2005-09-05 | - |
Source: ClinicalTrials.gov and EU CTIS, read 2026-10-03. Not medical advice.
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