GLP-1 receptor agonist
Liraglutide dose
Answer
FDA label for Liraglutide: The recommended starting dosage of liraglutide injection is 0.6 mg injected subcutaneously once daily for one week. Half-life on the label: approximately 13 hours. Trials with posted results tested 6 doses, most often 3 mg, 1.8 mg, 1.2 mg.
Not dosing advice.
FDA LABEL
What the approved labels state
Liraglutide ANDA218115 · label of 2026-07-27 Regulator
The recommended starting dosage of liraglutide injection is 0.6 mg injected subcutaneously once daily for one week.
The maximum recommended dosage of 1.8 mg injected subcutaneously once daily after at least one week of treatment with the 1.2 mg once daily dosage.
Half-life: approximately 13 hours (section 12.3).
Saxenda NDA206321 · label of 2026-02-25 Regulator
The recommended dose of SAXENDA is 3 mg daily.
Half-life: approximately 13 hours (section 12.3).
Victoza NDA022341 · label of 2025-10-14 Regulator
The recommended starting dosage of VICTOZA is 0.6 mg injected subcutaneously once daily for one week.
The maximum recommended dosage of 1.8 mg injected subcutaneously once daily after at least one week of treatment with the 1.2 mg once daily dosage.
Half-life: approximately 13 hours (section 12.3).
Xultophy 100/3.6 BLA208583 · label of 2025-10-14 Regulator
Recommended starting dose for patients naïve to basal insulin or GLP-1 receptor agonist 11 11 units 0.4 mg 12 12 units 0.43 mg 13 13 units 0.47 mg 14 14 units 0.5 mg 15 15 units 0.54 mg 16 16 units 0.58 mg Recommended starting dose for patients currently on basal insulin or GLP-1 receptor agonist 17 17 units 0.61 mg 18 18 units 0.65 mg 19 19 units 0.68 mg 20 20 units 0.72 mg 21 21 units 0.76 mg 22 22 units 0.79 mg 23 23 units 0.83 mg 24 24 units 0.86 mg 25 25 units 0.9 mg 26 26 units 0.94 mg 27 27 units 0.97 mg 28 28 units 1.01 mg 29 29 units 1.04 mg 30 30 units 1.08 mg 31 31 units 1.12 mg 32 32 units 1.15 mg 33 33 units 1.19 mg 34 34 units 1.22 mg 35 35 units 1.26 mg 36 36 units 1.3 mg 37 37 units 1.33 mg 38 38 units 1.37 mg 39 39 units 1.4 mg 40 40 units 1.44 mg 41 41 units 1.48 mg 42 42 units 1.51 mg 43 43 units 1.55 mg 44 44 units 1.58 mg 45 45 units 1.62 mg 46 46 units 1.66 mg 47 47 units 1.69 mg 48 48 units 1.73 mg 49 49 units 1.76 mg 50 50 units 1.8 mg Maximum daily dosage [see Warnings and Precautions ] * The dose counter on the XULTOPHY 100/3.6 pen displays numbers for the even units and displays lines for the odd units. 2.3 Titration of XULTOPHY 100/3.6.
Maximum daily dosage is 50 units (50 units of insulin degludec and 1.8 mg of liraglutide).
IN TRIALS
Doses tested in 144 trials with posted results
| Dose in the arm title | Trials | People on it | Phases |
|---|---|---|---|
| 3 mg | 12 | 4,292 | 2/3/4 |
| 1.8 mg | 13 | 3,338 | 2/3/4 |
| 1.2 mg | 6 | 1,000 | 2/3 |
| 0.6 mg | 3 | 625 | 2/3 |
| 0.9 mg | 4 | 624 | 3 |
| 0.3 mg | 1 | 64 | 2 |
Trial register Read from the titles of arms that received Liraglutide (n ≥ 20). An arm naming several doses counts under each; a schedule or escalation is on the trial record. All trials.
WEEKLY
Register Watch, weekly
New trials, approvals and enforcement actions. One email a week.