CXCR4 antagonist
Motixafortide dose
Answer
FDA label for APHEXDA: Recommended dosage is 1.25 mg/kg actual body weight by subcutaneous injection 10 to 14 hours prior to initiation of apheresis. Trials with posted results tested 2 doses, most often 2 mg/kg, 1.25 mg/kg.
Not dosing advice.
FDA LABEL
What the approved labels state
APHEXDA NDA217159 · label of 2026-06-04 Regulator
Recommended dosage is 1.25 mg/kg actual body weight by subcutaneous injection 10 to 14 hours prior to initiation of apheresis.
IN TRIALS
Doses tested in 2 trials with posted results
| Dose in the arm title | Trials | People on it | Phases |
|---|---|---|---|
| 2 mg/kg | 1 | 37 | 1 |
| 1.25 mg/kg | 1 | 36 | 1 |
Trial register Read from the titles of arms that received Motixafortide (n ≥ 20). An arm naming several doses counts under each; a schedule or escalation is on the trial record. All trials.
WEEKLY
Register Watch, weekly
New trials, approvals and enforcement actions. One email a week.