GLP-1 receptor agonist

Exenatide

US: FDA-approvedEU: WithdrawnUK: AuthorisedCA: AuthorisedAU: Status unknownCH: Not on the registerBR: RegistadoRS: Not on the registerSG: Not on the registerTR: Ruhsatli

Answer

Exenatide is authorised or registered in the US, the UK, Canada, Brazil and Turkey: 5 of the 10 registers read. Highest trial phase: Phase 2. It has 383 registered trials, 18 of them running. Brand names on the FDA label register: Byetta and Exenatide.

RegulatorTrial register10 regulators' registers, read 2026-09-03 to 2026-10-03 · ClinicalTrials.gov and EU CTIS, read 2026-10-03

Not medical, legal or regulatory advice.

Registered trials383Trial register ClinicalTrials.gov and EU CTIS
Running now18Trial register recruiting, active or enrolling
Results posted118Trial register with results on the register
Stopped early8.9%Trial register all peptides: 10%

383 trials by status

Trial register
Running 18Completed 273Stopped early 34Status unknown 52Other or not stated 6

ClinicalTrials.gov and EU CTIS · read 2026-10-03 · 118 trials have posted results

Trials first submitted per year

Trial register

ClinicalTrials.gov first-submitted date, last 10 years · read 2026-10-03. 2026 is not complete. 292 trials carry no first-submitted date (EU CTIS publishes none, or the year is outside this range).

Status by jurisdiction

World map
Authorised or registeredNot on the register, or withdrawnNot read yet, or status unknown
WhereStatusRegisterRead
United StatesFDA-approvedFDA, openfda2026-10-03
European UnionWithdrawnEMA, ema2026-10-03
United KingdomAuthorisedMHRA, uk-mhra2026-09-03
CanadaAuthorisedHealth Canada, ca-dpd2026-09-03
AustraliaStatus unknownTGA, au-artgnot read
SwitzerlandNot on the registerSwissmedic, ch-swissmedic2026-09-03
BrazilRegistadoANVISA, br-anvisa2026-09-03
SerbiaNot on the registerALIMS, rs-alims2026-09-03
SingaporeNot on the registerHSA, sg-hsa2026-09-03
TurkeyRuhsatliTITCK, tr-titck2026-09-03

An EU decision applies in the 30 territories the EU register covers: its member states, and Iceland, Liechtenstein and Norway. A dashed tile has no register read for this peptide.

Side effects

Trial register
24 placebo-controlled trials · 9,989 people on Exenatide · grey is placebo
Headache1.9% 1.3%
Non-cardiac chest pain1.1% 1%
Osteoarthritis0.9% 1%
Dizziness0.8% 0.4%
Constipation0.8% 0.3%
ClinicalTrials.gov posted results · read 2026-10-03All side effects

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REGISTERED TRIALS

Newest 10 of 383 trials

All 383 trials
NCT05663515
A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide a
currently recruiting participants · register updated 2026-09-24
NCT06725693
Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related Disease
currently recruiting participants · register updated 2026-09-08
NCT05220917
Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
running, but no longer enrolling · register updated 2026-08-13
NCT07702461
Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists
currently recruiting participants · register updated 2026-07-24
NCT07497399
Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis
currently recruiting participants · register updated 2026-07-17
NCT05356104
GLP-1 Analogue in Preventing Progression of Small Vessel Disease (GAPP-SVD)
currently recruiting participants · register updated 2026-06-05
NCT02860923
Efficacy and Safety of Exenatide in the Treatment of Hypothalamic Obesity After Craniopharyngioma Therapy
completed · register updated 2026-05-22
NCT02042664
Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG
completed · register updated 2026-05-07
NCT04232969
Exenatide Once Weekly Over 2 Years as a Potential Disease Modifying Treatment for Parkinson's Disease
completed · register updated 2026-05-06
NCT05482789
Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes
currently recruiting participants · register updated 2026-04-20

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