GLP-1 receptor agonist
Lixisenatide clinical trials
Answer
Lixisenatide has 75 registered trials: 6 running, 58 completed, 6 stopped early. 27 posted results.
Trial registerClinicalTrials.gov, read 2026-10-03
| Trial | Title | Status | Phase | Registered | Results |
|---|---|---|---|---|---|
| NCT05220917 Trial register | Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study | running, but no longer enrolling | - | 2021-12-22 | - |
| NCT06716424 Trial register | A Study to Investigate Safety and Efficacy of iGlarLixi in Adult Patients With Type 2 Diabetes Mellitus | completed | - | 2024-12-04 | - |
| NCT07307235 Trial register | Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China Population With Uncontrolled Type 2 Diabetes on Oral Agents | currently recruiting participants | - | 2025-12-29 | - |
| NCT06671587 Trial register | iGlarLixi CGM Study in Chinese T2D Individuals After OADs | currently recruiting participants | - | 2024-11-04 | - |
| NCT07173712 Trial register | Regimen Transition After Short-Term Intensive Insulin Therapy in Type 2 Diabetes | not yet recruiting participants | - | 2025-09-15 | - |
| NCT03439943 Trial register | Study to Evaluate the Effect of Lixisenatide in Patient With Parkinson's Disease | completed | - | 2018-02-20 | - |
| NCT05413369 Trial register | iGlarLixi vs IDegAsp in Chinese Participants After OAD(s) | completed | - | 2022-06-10 | Posted |
| NCT07188545 Trial register | Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Rea | running, but no longer enrolling | - | 2025-09-16 | - |
| NCT07117240 Trial register | Evaluation of the Efficacy and Safety of GLP-1 Receptor Agonist Therapy In Steroid-Induced Diabetes | enrolling by invitation only | - | 2025-08-12 | - |
| NCT05114590 Trial register | Effect of Soliqua 100/33 on Time in Range From Continuous Glucose Monitoring in Insulin-naive Patients With Very Uncontrolled Type 2 Diabetes Mellitus | completed | - | 2021-11-10 | Posted |
| NCT03492580 Trial register | A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants | completed | - | 2018-04-10 | - |
| NCT02049034 Trial register | Lixisenatide-The Effects on Glucose and Lipid Metabolism in Type 2 Diabetes | completed | - | 2014-01-29 | - |
| NCT06449235 Trial register | Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh | last verified some time ago; the register no longer confirms its status | - | 2024-06-07 | - |
| NCT05136287 Trial register | SEMAGLUTIDE VERSUS GLP-1 RECEPTOR AGONISTS. EFFECTIVENESS , SAFETY AND QUALITY OF LIFE IN PATIENTS WITH DIABETES MELLITUS 2. OBSERVATIONAL, PROSPECTIVE AND MULT | completed | - | 2021-11-29 | - |
| NCT05804513 Trial register | The Effect of Lixisenatide on the Effect of Pituitary Hormones | last verified some time ago; the register no longer confirms its status | - | 2023-04-07 | - |
| NCT02244164 Trial register | Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments. | terminated before completion | - | 2014-09-15 | - |
| NCT03798054 Trial register | Evaluation of Insulin Glargine/Lixisenatide Fixed Ratio Combination in Patients With Type 2 Diabetes Insufficiently Controlled With Oral Antidiabetic Drug(s) | completed | - | 2019-01-09 | - |
| NCT03798080 Trial register | Comparison of the Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Ratio Combination to Insulin Glargine in Patients With Type 2 Diabetes Insufficient | completed | - | 2019-01-09 | - |
| NCT02803918 Trial register | A Study on Safety, Pharmacokinetics and Pharmacodynamics of Lixisenatide in Pediatric Patients With Type 2 Diabetes Mellitus (T2DM) | completed | - | 2016-06-17 | - |
| NCT02941367 Trial register | Safety Assessment of Lyxumia (Lixisenatide) and Sulfonylurea as Add-on Treatment to Basal Insulin in Uncontrolled Patients With Type 2 Diabetes Mellitus Who Ele | completed | - | 2016-10-21 | - |
| NCT03529123 Trial register | Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes (LixiLan-India) | completed | - | 2018-05-18 | - |
| NCT03767543 Trial register | Study Comparing the Efficacy and Safety of Insulin Glargine (Basal Insulin)/Lixisenatide (GLP-1 Receptor Agonist) Combination (Soliqua™) in Patients With Type 2 | completed | - | 2018-12-06 | - |
| NCT03434119 Trial register | Efficacy and Safety of Soliqua Versus Lantus in Ethnically/Racially Diverse Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insulin and | terminated before completion | - | 2018-02-15 | Posted |
| NCT02787551 Trial register | Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FR | completed | - | 2016-06-01 | Posted |
| NCT03819790 Trial register | The Effect of Soliqua on Glucose Variability in Type 2 Patients Among South Asians | completed | - | 2019-01-29 | - |
| NCT03130426 Trial register | Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IGlarLixi | completed | - | 2017-04-23 | - |
| NCT04196231 Trial register | Durability of Combination of Insulin and GLP-1 Receptor Agonist or SGLT-2 Inhibitors Versus Basal Bolus Insulin Regimen in Type 2 Diabetes (BEYOND) | completed | - | 2019-12-06 | - |
| NCT03881995 Trial register | Effects of Insulin Glargine and Lixisenatide on the Brain | terminated before completion | - | 2019-03-20 | - |
| NCT02713477 Trial register | Postprandial Glucodynamic Response to Insulin Glargine/Lixisenatide Fixed Ratio Combination in Japanese Patients With Type 2 Diabetes Mellitus | completed | - | 2016-03-18 | - |
| NCT02749890 Trial register | Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (LixiLan) to Lixisenatide on Top of Oral Anti-diabetic Drugs (OADs) With Type 2 | completed | - | 2016-04-25 | - |
| NCT02752412 Trial register | Efficacy and Safety of LixiLan Versus Insulin Glargine Alone Both With Metformin in Japanese With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insu | completed | - | 2016-04-27 | - |
| NCT02752828 Trial register | Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (LixiLan) to Insulin Glargine Alone on Top of Oral Anti-diabetic Drugs (OADs) W | completed | - | 2016-04-27 | - |
| NCT02640118 Trial register | The Impact of Lixisenatide on Postprandial Glucose Tolerance in Pancreatectomised Subjects | completed | - | 2015-12-28 | - |
| NCT04184947 Trial register | Cardiovascular Outcomes SGLT-2 Inhibitors Versus GLP-1 Receptor Agonists | completed | - | 2019-12-01 | - |
| NCT03959865 Trial register | GLP-1 REceptor Agonists and Real World EvIdeNce | last verified some time ago; the register no longer confirms its status | - | 2019-05-20 | - |
| NCT02231658 Trial register | Effects of Victoza® Versus Lyxumia® on Gastroesophageal Reflux, Gastric Emptying and Gastric Acid Secretion | terminated before completion | - | 2014-09-04 | - |
| NCT02745470 Trial register | Effects of a GLP-1 Receptor Agonist on Functional Activation and Connectivity of the Brain | completed | - | 2016-04-20 | - |
| NCT02058147 Trial register | Efficacy and Safety of Insulin Glargine/ Lixisenatide Fixed Ratio Combination Compared to Insulin Glargine Alone and Lixisenatide Alone on Top of Metformin in P | completed | - | 2014-02-07 | Posted |
| NCT02058160 Trial register | Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes | completed | - | 2014-02-07 | Posted |
| NCT02168491 Trial register | Feasibility of Once/Daily Administered GLP/1 Receptoragonist (Lixisenatide) in Combination With Basal Insulin | completed | - | 2014-06-20 | Posted |
| NCT01798706 Trial register | Efficacy and Safety of Lixisenatide Versus Placebo on Top of Basal Insulin and/or Oral Antidiabetic Treatment in Older Type 2 Diabetic Patients | completed | - | 2013-02-26 | Posted |
| NCT02767596 Trial register | Evaluation of Lixisenatide Efficacy in Diabetes Mellitus Type 2 With Failure of Other GLP-1 Analog | terminated before completion | - | 2016-05-10 | - |
| NCT01476475 Trial register | Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic Patients | completed | - | 2011-11-22 | Posted |
| NCT01973231 Trial register | Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes | completed | - | 2013-10-31 | Posted |
| NCT02274740 Trial register | Effect of Lixisenatide on Postprandial Lipid Profile in Obese Type 2 Diabetic Patients | terminated before completion | - | 2014-10-24 | - |
| NCT01768559 Trial register | Efficacy and Safety of Lixisenatide Versus Insulin Glulisine on Top of Insulin Glargine With or Without Metformin in Type 2 Diabetic Patients | completed | - | 2013-01-15 | Posted |
| NCT00905255 Trial register | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation in Monotherapy (GETGOAL-MONO Japan LTS) | completed | - | 2009-05-20 | Posted |
| NCT01147250 Trial register | Evaluation of Cardiovascular Outcomes in Patients With Type 2 Diabetes After Acute Coronary Syndrome During Treatment With AVE0010 (Lixisenatide) | completed | - | 2010-06-22 | Posted |
| NCT00712673 Trial register | GLP-1 Receptor Agonist Lixisenatide (Morning or Evening) in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin | completed | - | 2008-07-10 | Posted |
| NCT00713830 Trial register | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Sulfonylurea | completed | - | 2008-07-14 | Posted |
| NCT00763451 Trial register | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin | completed | - | 2008-10-01 | Posted |
| NCT00688701 Trial register | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation in Monotherapy | completed | - | 2008-06-03 | Posted |
| NCT00707031 Trial register | GLP-1 Receptor Agonist Lixisenatide Versus Exenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin | completed | - | 2008-06-30 | Posted |
| NCT00715624 Trial register | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Basal Insulin | completed | - | 2008-07-15 | Posted |
| NCT00763815 Trial register | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Pioglitazone | completed | - | 2008-10-01 | Posted |
| NCT01175473 Trial register | Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes | completed | - | 2010-08-04 | Posted |
| NCT01517412 Trial register | Comparison of Lixisenatide Injected Prior to the Main Meal of the Day Versus Prior to Breakfast in Type 2 Diabetic Patients on Metformin | completed | - | 2012-01-25 | Posted |
| NCT01596504 Trial register | Pharmacodynamic Effects of Lixisenatide Compared to Liraglutide in Patients With Type 2 Diabetes Not Adequately Controlled With Insulin Glargine With or Without | completed | - | 2012-05-11 | Posted |
| NCT01169779 Trial register | Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled by Metformin | completed | - | 2010-07-26 | Posted |
| NCT00866658 Trial register | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Basal Insulin +/- Sulfonylurea (GETGO | completed | - | 2009-03-20 | Posted |
| NCT00975286 Trial register | 24-week Treatment With Lixisenatide in Type 2 Diabetes Insufficiently Controlled With Metformin and Insulin Glargine | completed | - | 2009-09-11 | Posted |
| NCT00976937 Trial register | 24-week Study Comparing Lixisenatide to Sitagliptin as add-on to Metformin in Obese Type 2 Diabetic Patients Younger Than 50 Years | completed | - | 2009-09-15 | Posted |
| NCT02200991 Trial register | Effect of Lixisenatide on Postprandial Plasma Glucose Compared to Sitagliptin in Combination With Insulin Glargine | completed | - | 2014-07-25 | - |
| NCT02276196 Trial register | Effect of LIXIsenatide on the Renal System | completed | - | 2014-10-28 | - |
| NCT02020629 Trial register | Study on Lixisenatide and Counterregulation to Hypoglycemia | completed | - | 2013-12-25 | - |
| NCT02308254 Trial register | Drug Trial of Lixisenatide on Gastric Emptying and Blood Pressure Drops in Type 2 Diabetics and Healthy People | last verified some time ago; the register no longer confirms its status | - | 2014-12-04 | - |
| NCT01940965 Trial register | Safety and Tolerability of Lixisenatide in Combination With Oral Anti-Diabetic Treatment in Patients With Type 2 Diabetes | completed | - | 2013-09-12 | - |
| NCT02501850 Trial register | The Effect of the GLP-1 Receptor Agonists on Blood Levels of Lipoprotein (a) | last verified some time ago; the register no longer confirms its status | - | 2015-07-17 | - |
| NCT01632163 Trial register | Assessment of the Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Insufficiently Controlled With Basal Insulin +/- Metformin | completed | - | 2012-07-02 | - |
| NCT01960179 Trial register | Safety And Tolerability Of Lixisenatide In Monotherapy In Patients With Type 2 Diabetes | completed | - | 2013-10-10 | - |
| NCT01910194 Trial register | Impact of Combined of Lantus(Insulin Glargine) and Lyxumia (Lixisenatide) on Insulin Secretion and Gastric Emptying | completed | - | 2013-07-29 | - |
| NCT01572649 Trial register | Evaluation of the Blood Levels of the Drug (Lixisenatide), the Plasma Glucose Levels and Safety in Paediatric and Adult Patients With Type 2 Diabetes | completed | - | 2012-04-06 | - |
| NCT00299871 Trial register | Dose Ranging Study of the GLP-1 Agonist AVE0010 in Metformin-Treated Subjects With Type 2 Diabetes Mellitus | completed | - | 2006-03-07 | - |
| NCT00931372 Trial register | Lixisenatide for Restoration of Insulin Release in Subjects With Diabetes Mellitus Type 2 | completed | - | 2009-07-02 | - |
| NCT01146678 Trial register | Relative Bioavailability and Activity of Different Formulations of Insulin Glargine and Lixisenatide in Patients With Diabetes Mellitus Type 1 | completed | - | 2010-06-17 | - |
Source: ClinicalTrials.gov, read 2026-10-03. Not medical advice.
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