amylin analogue

Pramlintide clinical trials

Answer

Pramlintide has 65 registered trials: 5 running, 44 completed, 9 stopped early. 15 posted results.

Trial registerClinicalTrials.gov and EU CTIS, read 2026-10-03

TrialTitleStatusPhaseRegisteredResults
NCT07679516
Trial register
Postprandial Regulation of Bone Perfusion in Healthy Individualsnot yet recruiting participants-2026-07-01-
NCT06422325
Trial register
Two Way Crossover Closed Loop Study Insulin vs Insulin and Pramlintidecompleted-2024-05-20Posted
NCT03560960
Trial register
Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Diseaserunning, but no longer enrolling-2018-06-19-
NCT06619015
Trial register
Tailoring Obesity Treatment Trialwithdrawn before enrolling anyone-2024-10-01-
NCT07506369
Trial register
Pancreatic Polypeptide as a Modulator of Amylin- Induced Satiety in Healthy Humanscurrently recruiting participants-2026-04-01-
NCT07340775
Trial register
Hypersensitivity to Amylin in Post-Traumatic Headachenot yet recruiting participants-2026-01-05-
NCT07340788
Trial register
Amylin-Induced Migraine Attacks Without Auranot yet recruiting participants-2026-01-05-
2024-510802-10-00
Trial register
The impact of pramlintide on top of semaglutide in obese people with prediabetesNot stated2/3--
NCT06046417
Trial register
A Fully Automated Lyumjev and Pramlintide Delivery System for Adults With Type 1 Diabeteslast verified some time ago; the register no longer confirms its status-2023-09-21-
NCT04074317
Trial register
Phase 2, Randomized, Open-Label, Crossover, PD/PK Study of a Novel Pram-Insulin Co-Formulation in Adults With T1Dcompleted-2019-08-30Posted
NCT06186063
Trial register
The Role of Amylin in Bone Metabolismlast verified some time ago; the register no longer confirms its status-2023-12-29-
NCT05199714
Trial register
A Fully-closed Loop, Pramlintide and Insulin, Artificial Pancreas Clinical Trial for Adults With Type 1 Diabetescompleted-2022-01-20-
NCT01841359
Trial register
Pramlintide (Symlin) for the Treatment of Hypoglycemia Following Gastric Bypass Surgerycompleted-2013-04-26Posted
NCT04252612
Trial register
Biological Outcomes of Pramlintide in Resectable Cutaneous Squamous Cell Carcinoma: A Pilot Studywithdrawn before enrolling anyone-2020-02-05-
NCT04243629
Trial register
Co-administration of Pramlintide and Insulin Via an Automated Dual-hormone Artificial Pancreas System in Adults With Type 1 Diabeteslast verified some time ago; the register no longer confirms its status-2020-01-28-
NCT00691158
Trial register
A Study of the Functional Magnetic Resonance Imaging Response to Leptin and Pramlintidelast verified some time ago; the register no longer confirms its status-2008-06-05-
NCT04163874
Trial register
Alleviating Carbohydrate Counting for Patients With Type 1 Diabetes Using a Novel Insulin-plus-pramlintide Artificial Pancreascompleted-2019-11-15-
NCT03547427
Trial register
Glucagon Counterregulation in Type 1 Diabetesterminated before completion-2018-06-06-
NCT04972175
Trial register
Safety and Efficacy of BC LisPramlast verified some time ago; the register no longer confirms its status-2021-07-15-
NCT00732147
Trial register
Effects of Pramlintide on Endogenous Production of Very-low-density-lipoprotein (VLDL)-Triglyceride and Glucose in the Post Prandial State in T2DMwithdrawn before enrolling anyone-2008-08-11-
NCT03800875
Trial register
Insulin-plus-pramlintide Closed-loop Strategy to Regulate Glucose Levels Without Carbohydrate Countingcompleted-2019-01-11-
NCT03993366
Trial register
Pramlintide and Fiasp Closed-Loop With a Simple Meal Announcementcompleted-2019-06-20-
NCT03981627
Trial register
A Trial to Assess Safety and Efficacy of ADO09 Versus Insulin Aspart in Subjects With Type 1 Diabetes Mellituscompleted-2019-06-07-
NCT00790699
Trial register
Safety Study of Using Symlin Alongside Insulin in a Multiple Injection Portterminated before completion-2008-11-10Posted
NCT03598075
Trial register
Amylin and CGRP Head to Head Provocation in Migraine Without Aura Patientscompleted-2018-07-26-
NCT02814123
Trial register
Effect of Basal-Bolus Closed-Loop Co-Administration of Insulin and Pramlintide on Improving the Glycemic Control in Type 1 Diabetescompleted-2016-06-27-
NCT03916640
Trial register
A Trial to Assess a Co-formulation of an Insulin Analog and Pramlintide in Subjects With Type 1 Diabetes Mellituscompleted-2019-04-16-
NCT03512236
Trial register
A Trial to Investigate Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BioChaperone® Pramlintide Insulin in Patients With Type 1 Diabetes Mellitucompleted-2018-04-30-
NCT00505882
Trial register
Efficacy of Pramlintide on Prevention of Weight Gain Early Onset of Type 1 Diabeteswithdrawn before enrolling anyone-2007-07-25-
NCT00690235
Trial register
Demonstrate the Effects of Pramlintide on Weight Reduction in Schizophreniacompleted-2008-06-04Posted
NCT02500979
Trial register
Effect of a Fixed Pramlintide: Insulin Dose Ratio on Postprandial Glucose in Type 1 Diabetes Mellituscompleted-2015-07-17Posted
NCT01165944
Trial register
Effectiveness Study of Pramlintide to Treat Post-Transplant Diabetes Mellituswithdrawn before enrolling anyone-2010-07-20-
NCT00442767
Trial register
Post-meal Insulin Dosing With Adjuvant Pre-meal Pramlintide in Children With Type 1 Diabetes Mellituscompleted-2007-03-02Posted
NCT01269047
Trial register
Use of Exenatide and Pramlintide to Decrease Post-prandial Hyperglycemiacompleted-2011-01-04Posted
NCT01269008
Trial register
Closed Loop System With Pramlintide Versus Exenatidecompleted-2011-01-04-
NCT00950677
Trial register
The Effect of Byetta and Symlin on Post-meal Meal Blood Sugar Levels in Children With Type 2 Diabetescompleted-2009-08-03-
NCT00206258
Trial register
The Role of Amylin and Glucagon in T1DMcompleted-2005-09-21-
NCT00206297
Trial register
The Effect of Prolonged Pramlintide Infusion in Pediatric Diabetescompleted-2005-09-21-
NCT00291772
Trial register
Continuous Subcutaneous Infusion of Pramlintide and Insulincompleted-2006-02-15-
NCT00042601
Trial register
Evaluation of the Effect of Pramlintide on Satiety and Food Intakecompleted-2002-08-05-
NCT00042458
Trial register
Evaluation of Dose-titration of Pramlintide During Initiation of Therapy in Patients Trying to Improve Glucose Controlcompleted-2002-08-01-
NCT00042471
Trial register
Evaluation of the Bioavailability of Pramlintidecompleted-2002-08-01-
NCT00107107
Trial register
Study of the Long-Term Safety of Pramlintide in Subjects With Type 1 Diabetes Mellituscompleted-2005-04-06-
NCT00842075
Trial register
Pramlintide in Adolescents With Type 1 Diabetescompleted-2009-02-12Posted
NCT00189514
Trial register
A Study to Examine the Long Term Effect of Pramlintide on Body Weight and Its Safety and Tolerability in Obese Subjectscompleted-2005-09-19-
NCT00444561
Trial register
Exploratory Study to Evaluate Various Pharmacodynamic Effects of Subcutaneously Infused or Injected Pramlintide in Obese Subjectscompleted-2007-03-08-
NCT00044707
Trial register
Evaluation of an Orally Administered Medication When Taken in Conjunction With Pramlintidecompleted-2002-09-05-
NCT00108004
Trial register
Clinical Utility and Safety of Pramlintide in Subjects With Type 1 and Type 2 Diabetes Mellituscompleted-2005-04-13-
NCT00673387
Trial register
Study to Examine Safety, Tolerability, and Effect on Body Weight of Metreleptin Administered in Conjunction With Pramlintide in Obese and Overweight Subjectscompleted-2008-05-07Posted
NCT00819234
Trial register
Extension Study of Protocol DFA102 to Examine the Long-Term Safety, Tolerability, and Effect on Body Weight of Pramlintide Administered in Combination With Metrcompleted-2009-01-08Posted
NCT01235741
Trial register
A Study To Examine The Efficacy And Safety Of Pramlintide+Metreleptin In Obese Subjectsterminated before completion-2010-11-08Posted
NCT00392925
Trial register
A Study to Evaluate the Effect on Body Weight of Leptin Administered in Conjunction With Pramlintide in Overweight and Obese Subjectscompleted-2006-10-26Posted
NCT00467649
Trial register
A Study to Characterize Regimens of Basal Insulin Intensified With Either Symlin® or Rapid Acting Insulin in Patients With Type 2 Diabetescompleted-2007-05-01Posted
NCT00112021
Trial register
A Study to Examine the Effect of Pramlintide on Body Weight and Its Safety and Tolerability in Obese Subjectscompleted-2005-05-30-
NCT00240253
Trial register
A Study Evaluating the Efficacy and Safety of Adding Symlin® to Lantus® (Insulin Glargine) in Subjects With Type 2 Diabetescompleted-2005-10-18-
NCT00229658
Trial register
An Observational Study Evaluating SYMLIN® (Pramlintide Acetate) Injection Use in Insulin Using Patients With Type 2 and Type 1 Diabetescompleted-2005-09-30Posted
NCT00313183
Trial register
A Study to Evaluate Symlin in Adolescent Subjects With Type 1 Diabetes Mellituscompleted-2006-04-12-
NCT00402077
Trial register
A Study to Examine the Safety, Tolerability, and Body Weight Effect of Pramlintide Alone and in Combination With Oral Antiobesity Agents in Overweight and Obesecompleted-2006-11-22-
NCT01708044
Trial register
Effect of Different Fixed Pramlintide:Insulin Dose Ratios on Postprandial Glucose in T1DMcompleted-2012-10-16-
NCT01434862
Trial register
Pramlintide Combined With Model Predictive Control Algorithmterminated before completion-2011-09-15-
NCT01839370
Trial register
Phase 2 Study of Adaptive Insulin Meal Supervisor (AIMS) in Adults With Type 1 Diabetes Mellituscompleted-2013-04-24-
NCT00502138
Trial register
A Pilot Study of Continuous Subcutaneous Pramlintide Infusion Therapy in Patients With Type 1 Diabetescompleted-2007-07-17-
NCT01137695
Trial register
Efficacy Study of High Dose Symlin to Treat Type 2 Diabetes Mellituslast verified some time ago; the register no longer confirms its status-2010-06-04-
NCT00460304
Trial register
The Effect of Pramlintide on Meal Time Insulin Boluscompleted-2007-04-13-
NCT00489645
Trial register
Effect of Hyperglycemia on Gastric Emptying Interactions With Pramlintidecompleted-2007-06-21-

Source: ClinicalTrials.gov and EU CTIS, read 2026-10-03. Not medical advice.

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