| 2026-04-16 | Action | Ohio Board of Pharmacy: board | Regulator Ohio Board of Pharmacy |
| 2026-03-12 | Trial | New trial registered: Clinical Trial in Patients With Barth Syndrome- 4TAZPower | Trial register ClinicalTrials.gov |
| 2025-12-12 | Results | Results posted: FRDA Investigator Initiated Study (IIS) With Elamipretide | Trial register ClinicalTrials.gov |
| 2025-10-15 | Trial | New trial registered: Study of Healthy Aging and Physical Function With Elamipretide | Trial register ClinicalTrials.gov |
| 2024-04-16 | Results | Results posted: A Trial to Evaluate Safety, Tolerability and Efficacy of Elamipretide in Subjects With Barth Syndrome | Trial register ClinicalTrials.gov |
| 2024-04-16 | Trial | New trial registered: ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degen | Trial register ClinicalTrials.gov |
| 2023-10-17 | Results | Results posted: ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GA | Trial register ClinicalTrials.gov |
| 2021-12-17 | Results | Results posted: Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondr | Trial register ClinicalTrials.gov |
| 2021-12-09 | Trial | New trial registered: FRDA Investigator Initiated Study (IIS) With Elamipretide | Trial register ClinicalTrials.gov |
| 2021-12-08 | Trial | New trial registered: Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) | Trial register ClinicalTrials.gov |
| 2021-10-12 | Results | Results posted: A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropa | Trial register ClinicalTrials.gov |
| 2021-09-17 | Results | Results posted: A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial D | Trial register ClinicalTrials.gov |
| 2021-04-02 | Results | Results posted: A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension | Trial register ClinicalTrials.gov |
| 2020-12-23 | Trial | New trial registered: An Intermediate Size Expanded Access Protocol of Elamipretide | Trial register ClinicalTrials.gov |
| 2020-09-21 | Results | Results posted: An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macul | Trial register ClinicalTrials.gov |
| 2020-08-11 | Results | Results posted: Effects of Intravenous Bendavia™ on Reperfusion Injury in Patients Undergoing Angioplasty of the Renal Artery | Trial register ClinicalTrials.gov |
| 2020-07-07 | Results | Results posted: Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study | Trial register ClinicalTrials.gov |
| 2020-06-23 | Results | Results posted: A Phase 2 Study to Evaluate the Impact of MTP-131 (Bendavia™) on Skeletal Muscle Function in Elderly | Trial register ClinicalTrials.gov |
| 2020-06-11 | Results | Results posted: Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Events | Trial register ClinicalTrials.gov |
| 2020-04-22 | Results | Results posted: Effect of Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Reduced Ejection Fraction | Trial register ClinicalTrials.gov |
| 2019-12-27 | Results | Results posted: Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial Myopathy | Trial register ClinicalTrials.gov |
| 2019-03-25 | Trial | New trial registered: ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GA | Trial register ClinicalTrials.gov |
| 2017-10-12 | Trial | New trial registered: A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension | Trial register ClinicalTrials.gov |
| 2017-03-21 | Trial | New trial registered: A Trial to Evaluate Safety, Tolerability and Efficacy of Elamipretide in Subjects With Barth Syndrome | Trial register ClinicalTrials.gov |
| 2016-11-18 | Trial | New trial registered: Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mito | Trial register ClinicalTrials.gov |
| 2016-09-14 | Trial | New trial registered: A Phase 2 Study to Evaluate the Cardiac and Renal Effects of Short Term Treatment With Elamipretide in Patients Hospitalized With Congestion Due to | Trial register ClinicalTrials.gov |
| 2016-07-25 | Trial | New trial registered: An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related | Trial register ClinicalTrials.gov |
| 2016-06-13 | Trial | New trial registered: Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study | Trial register ClinicalTrials.gov |
| 2016-06-08 | Trial | New trial registered: A Study to Evaluate the Effects of 4 Weeks Treatment With Subcutaneous Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failu | Trial register ClinicalTrials.gov |
| 2016-05-27 | Trial | New trial registered: Effect of Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Reduced Ejection Fraction | Trial register ClinicalTrials.gov |
| 2016-02-15 | Trial | New trial registered: A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic N | Trial register ClinicalTrials.gov |
| 2015-12-20 | Trial | New trial registered: A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothe | Trial register ClinicalTrials.gov |
| 2015-04-30 | Trial | New trial registered: A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Functio | Trial register ClinicalTrials.gov |
| 2015-03-01 | Trial | New trial registered: A Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of Bendavia™ (MTP-131) in Patients With Heart Fa | Trial register ClinicalTrials.gov |
| 2015-03-01 | Trial | New trial registered: A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart Failure | Trial register ClinicalTrials.gov |
| 2015-02-09 | Trial | New trial registered: Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial Myopathy | Trial register ClinicalTrials.gov |
| 2014-12-02 | Trial | New trial registered: A Study of MTP-131 Topical Ophthalmic Solution in Subjects With Diabetic Macular Edema and Non-Exudative Intermediate Age-related Macular Degenerati | Trial register ClinicalTrials.gov |
| 2014-09-17 | Trial | New trial registered: A Phase 2 Study to Evaluate the Impact of MTP-131 (Bendavia™) on Skeletal Muscle Function in Elderly | Trial register ClinicalTrials.gov |
| 2013-02-06 | Trial | New trial registered: Safety and Pharmacokinetic (PK) Study of Oral Bendavia Administered for 7 Days | Trial register ClinicalTrials.gov |
| 2012-12-19 | Trial | New trial registered: Effects of Intravenous Bendavia™ on Reperfusion Injury in Patients Undergoing Angioplasty of the Renal Artery | Trial register ClinicalTrials.gov |
| 2012-12-18 | Trial | New trial registered: A Phase 1 Study Examining the Pharmacokinetics and Tolerability of a Single Oral Dose of Bendavia (MTP-131) | Trial register ClinicalTrials.gov |
| 2012-03-28 | Trial | New trial registered: Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Events | Trial register ClinicalTrials.gov |
| 2012-01-23 | Trial | New trial registered: The Impact of Intravenous Bendavia™ on Endothelial Reactivity Dysfunction in Cigarette Smoking | Trial register ClinicalTrials.gov |
| 2012-01-06 | Trial | New trial registered: Study to Assess the Pharmacodynamic Effects of Unfractionated Heparin (UFH) in Healthy Volunteers With and Without Bendavia | Trial register ClinicalTrials.gov |
| 2010-04-30 | Trial | New trial registered: Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of Intravenous (IV) Infusion of MTP-131 (Bendavia™) in Healthy Adults | Trial register ClinicalTrials.gov |