vasopressin analogue
Terlipressin clinical trials
Answer
Terlipressin has 118 registered trials: 15 running, 54 completed, 10 stopped early. 7 posted results.
Trial registerClinicalTrials.gov and EU CTIS, read 2026-10-03
| Trial | Title | Status | Phase | Registered | Results |
|---|---|---|---|---|---|
| NCT07252401 Trial register | Terlipressin vs. Somatostatin in Cirrhotic Patients With Acute Variceal Bleeding and Renal Dysfunction | not yet recruiting participants | - | 2025-11-26 | - |
| NCT07746349 Trial register | Terlipressin vs Placebo to Reduce Bleeding in Fibroid Surgery | not yet recruiting participants | - | 2026-08-05 | - |
| NCT07719933 Trial register | Intraoperative Continuous Terlipressin Infusion is Associated With Reduced Severe Postoperative Complications After Laparoscopic Hepatectomy: a Prospective Prop | completed | - | 2026-07-22 | - |
| NCT02473341 Trial register | Efficacy Of Bovine Colostrum In The Treatment Of Severe Alcohol-Associated Hepatitis: A Randomized Controlled Trial | running, but no longer enrolling | - | 2015-06-08 | - |
| NCT06855758 Trial register | Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation | running, but no longer enrolling | - | 2025-03-04 | - |
| NCT02970175 Trial register | Interest of in Situ Terlipressin Administration Before the Realisation of Bronchial Biopsy | completed | - | 2016-11-21 | - |
| NCT07304466 Trial register | Effects of Terlipressin and Somatostatin on Portal Pressure in Patients Undergoing Living Donor Liver Transplantation | currently recruiting participants | - | 2025-12-26 | - |
| NCT04961528 Trial register | ACid Tranexamic or Terlipressin for Initial Emergency Treatment of Mild to seVere hEmoptysis: a Randomized Trial. | completed | - | 2021-07-14 | - |
| NCT06256432 Trial register | Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome | running, but no longer enrolling | - | 2024-02-13 | - |
| NCT07178366 Trial register | Double Plasma Separation and Adsorption in Acute-on-Chronic Liver Failure (DPMAS-ACLF Trial) | not yet recruiting participants | - | 2025-09-11 | - |
| NCT07460908 Trial register | Comparison of Terlipressin Versus Octreotide in Patients With Hepatorenal Syndrome | completed | - | 2026-03-10 | - |
| NCT06161766 Trial register | Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease | completed | - | 2023-12-08 | - |
| NCT05490888 Trial register | Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics | currently recruiting participants | - | 2022-07-28 | - |
| NCT07131306 Trial register | National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem Cell Therapy in Non-viral Acute on Chronic Liver Failure | not yet recruiting participants | - | 2025-07-11 | - |
| NCT07075315 Trial register | National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem-Cell (MSC) Therapy in Non-viral Acute on Chronic Liver Fa | not yet recruiting participants | - | 2025-07-11 | - |
| 2024-515010-40-00 Trial register | AcTIVE - ACid tranexamic or Terlipressin for Initial emergency treatment of mild to seVere hEmoptysis: a randomized Trial | Not stated | 3 | - | - |
| NCT06815770 Trial register | Efficacy and Safety of Continuous Infusion of Terlipressin vs Bolus Terlipressin in ACLF Patients With Acute Esophageal Variceal Bleed | not yet recruiting participants | - | 2025-02-07 | - |
| NCT05346393 Trial register | HRS-AKI Treatment With TIPS in Patients With Cirrhosis | currently recruiting participants | - | 2022-04-01 | - |
| 2023-503504-88-00 Trial register | A Single-blind, Phase 2, Multi-center, Randomized Study to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of the Relaxin Agonist R2R01 Plus Terlipre | Not stated | 2 | - | - |
| NCT04460560 Trial register | Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE) | completed | - | 2020-07-07 | Posted |
| 2024-514149-12-00 Trial register | Double blind randomized clinical trial comparing noradrenaline plus placebo versus noradrenaline plus terlipressin in septic shock. | Not stated | 3 | - | - |
| NCT06556472 Trial register | Safety and Efficacy of Continuous Infusion of Terlipressin With Norepinephrine Versus Norepinephrine Alone in Improving Outcomes of Acute Kidney Injury in Acute | last verified some time ago; the register no longer confirms its status | - | 2024-08-16 | - |
| NCT05154279 Trial register | The Effect of Intramyometrial Injection of Terlipressin Versus Intramyometrial Injection of Carbitocin on Hemoglobin and Blood Loss During Laparoscopic Myomecto | last verified some time ago; the register no longer confirms its status | - | 2021-12-13 | - |
| NCT05170230 Trial register | The Effect of Intracapsular Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Laparoscopic Myomectomy Operations | last verified some time ago; the register no longer confirms its status | - | 2021-12-27 | - |
| NCT05242783 Trial register | The Effect of Intramyometrial Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Open Myomectomy Operations Using Haemostatic Tourn | completed | - | 2022-02-16 | - |
| NCT03279419 Trial register | Thermal Imaging in Liver Disease. | completed | - | 2017-09-08 | - |
| NCT04112199 Trial register | A Study for Evaluation of BIV201 to Reduce Ascites and Complications in Patients With Cirrhosis and Refractory Ascites | terminated before completion | - | 2019-09-30 | - |
| NCT03130127 Trial register | Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver Cirrhosis | last verified some time ago; the register no longer confirms its status | - | 2017-04-26 | - |
| NCT05774067 Trial register | Noradrenaline Versus Glypressin for Prevention of Hypotension After Deflation of Tourniquet in Knee Arthroplasty | completed | - | 2023-03-07 | - |
| NCT06122753 Trial register | Preemptive TIPS for Variceal Bleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis | not yet recruiting participants | - | 2023-11-03 | - |
| NCT06122792 Trial register | Preemptive TIPS for Gastric Variceal Bleeding in Patients With Cirrhosis | not yet recruiting participants | - | 2023-11-03 | - |
| NCT06108362 Trial register | Effect of Terlipressin on the Incidence of Early Postoperative Acute Kidney Injury in Liver Transplantation Patients | last verified some time ago; the register no longer confirms its status | - | 2023-10-31 | - |
| NCT05875948 Trial register | Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome | last verified some time ago; the register no longer confirms its status | - | 2023-05-25 | - |
| NCT06027970 Trial register | Efficacy of Continuous Terlipressin Therapy After Endoscopic Variceal Ligation | last verified some time ago; the register no longer confirms its status | - | 2023-09-07 | - |
| NCT05699824 Trial register | To Study the Hemodynamic Response of Early Addition of Carvedilol to Terlipressin in Acute Variceal Bleed in Child's B and C Cirrhosis | last verified some time ago; the register no longer confirms its status | - | 2023-01-26 | - |
| NCT03572088 Trial register | Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion Needs | completed | - | 2018-06-28 | - |
| NCT03822091 Trial register | Terlipressin Infusion Alone Vs Terlipressin With Noradrenaline Infusion In The Treatment of Hepatorenal Syndrome Type 1 | completed | - | 2019-01-30 | - |
| NCT05434286 Trial register | Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Hepatorenal Syndrome-Acute Kidney In | last verified some time ago; the register no longer confirms its status | - | 2022-06-13 | - |
| NCT05207280 Trial register | Clinical Trial Comparing Noradrenaline (NA) Plus Placebo Versus Noradrenaline Plus Terlipressin (TP) in Septic Shock | last verified some time ago; the register no longer confirms its status | - | 2022-01-26 | - |
| NCT05806307 Trial register | Methods Decreasing Bleeding in Open Myomectomy | last verified some time ago; the register no longer confirms its status | - | 2023-04-10 | - |
| NCT04416282 Trial register | Efficacy of Early Terlipressin Plus Albumin Therapy in Comparison to Standard Treatment for HRS-AKI in Acute-on-chronic Liver Failure. | completed | - | 2020-06-04 | - |
| NCT01143246 Trial register | A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin | completed | - | 2010-06-14 | Posted |
| NCT02770716 Trial register | Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1 | completed | - | 2016-05-12 | Posted |
| NCT05331768 Trial register | Comparison of Endoscopic Band Ligation Plus 24-hour Versus 72-hour Terlipressin Therapy | completed | - | 2022-04-18 | - |
| NCT05315557 Trial register | Efficacy and Safety of Vasopressin Versus Terlipressin as a Second Vasopressor in Critically Ill Cirrhotics With Septic Shock- the VITEL-C Trial | last verified some time ago; the register no longer confirms its status | - | 2022-04-07 | - |
| NCT05266534 Trial register | The Effect of Intramyometrial Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Open Myomectomy Operations Without Using Haemostat | currently recruiting participants | - | 2022-03-04 | - |
| NCT04819568 Trial register | Comparison of Bolus Versus Continuous Infusion of Terlipressin Cirrhotic Patients With Septic Shock. | last verified some time ago; the register no longer confirms its status | - | 2021-03-29 | - |
| NCT05080543 Trial register | Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic Patients | last verified some time ago; the register no longer confirms its status | - | 2021-10-15 | - |
| NCT04339868 Trial register | Terlipressin for Refractory Septic Shock | last verified some time ago; the register no longer confirms its status | - | 2020-04-09 | - |
| NCT04028323 Trial register | Functional MRI-based Assessment of Terlipressin vs. Octreotide on Renal Function in Cirrhotic Patients With Acute Variceal Bleeding (CHESS1903) | last verified some time ago; the register no longer confirms its status | - | 2019-07-22 | - |
| NCT03483272 Trial register | MRI to Assess the Effect of Terlipressin in Patients With Acute Hepatorenal Syndrome (HRS-AKI) | completed | - | 2018-03-30 | - |
| NCT03107091 Trial register | Continuous Infusion Terlipressin for Patients With Cirrhosis and Refractory Ascites | completed | - | 2017-04-11 | Posted |
| NCT04948372 Trial register | Effects of Terlipressin on Renal Perfusion in Patients With Septic Shock | completed | - | 2021-07-01 | - |
| NCT04358016 Trial register | Terlipression Prevent Developing of Acute Kidney Injury During Upper-gastroentestinal Bleeding | completed | - | 2020-04-22 | - |
| NCT04353193 Trial register | Hemodynamic Profile of Terlipressin and Octreotide in Patients With Cirrhosis and Portal Hypertension. A Randomised, Single Blinded Clinical Trial. | last verified some time ago; the register no longer confirms its status | - | 2020-04-20 | - |
| NCT04221672 Trial register | The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy | last verified some time ago; the register no longer confirms its status | - | 2020-01-09 | - |
| NCT03584087 Trial register | Efficacy of Terlipressin Therapy in Acute Variceal Haemorrhage After EVL | completed | - | 2018-07-12 | - |
| NCT04110418 Trial register | Methylene Blue Versus Vasopressin Analogue for Treatment of Septic Shock in Preterm Neonate | last verified some time ago; the register no longer confirms its status | - | 2019-10-01 | - |
| NCT02695862 Trial register | To Assess Safety and Efficacy of Bolus Versus Continuous Infusion of Terlipressin in Acute Variceal Bleeding | completed | - | 2016-03-01 | - |
| NCT04056806 Trial register | 2- Day vs. 5- Day Terlipressin and Ceftriaxone in the Control Acute Gastroesophageal Variceal Hemorrhage | last verified some time ago; the register no longer confirms its status | - | 2019-08-14 | - |
| NCT04028505 Trial register | Terlipressin Infusion in Variceal Hemorrhage | last verified some time ago; the register no longer confirms its status | - | 2019-07-22 | - |
| NCT04013113 Trial register | Efficacy and Safety of Hemoperfusion or Plasma Exchange Compared to Standard Medical Therapy in Patients With Acute on Chronic Liver Failure | last verified some time ago; the register no longer confirms its status | - | 2019-07-05 | - |
| NCT03846180 Trial register | Terlipressin on Effect of Renal Function in Cirrhotic Patients With Acute Gastrointestinal Hemorrhage | completed | - | 2019-02-19 | - |
| NCT02726620 Trial register | Decision Support for Intraoperative Low Blood Pressure | completed | - | 2016-04-04 | Posted |
| NCT02377141 Trial register | Early Use of TIPSS in Patients With Cirrhosis and Variceal Bleeding | completed | - | 2015-02-05 | - |
| NCT01370161 Trial register | Early TIPS With Polytetrafluoroethylene (PTFE) Covered Stents for Acute Variceal Bleeding in Patients With Advanced Cirrhosis | completed | - | 2011-06-07 | - |
| NCT03395574 Trial register | Effect of Terlipressin on Cerebral Oxygen Saturation During Liver Transplantation | completed | - | 2018-01-10 | - |
| NCT03162419 Trial register | To Assess the Efficacy of High-Volume Plasma Exchange and GCSF Versus GCSF Alone in Patients of Acute on Chronic Liver Failure (ACLF). | withdrawn before enrolling anyone | - | 2017-04-20 | - |
| NCT03336814 Trial register | Evaluation of Early Association of Terlipressin and Norepinephrine During Septic Shock; the TerliNor Study | last verified some time ago; the register no longer confirms its status | - | 2017-11-08 | - |
| NCT03144713 Trial register | Efficacy and Safety of Terlipressin With Albumin Versus Midodrine With Albumin Versus Albumin Alone in Prevention of Paracentesis Induced Circulatory Dysfunctio | completed | - | 2017-05-09 | - |
| NCT03038503 Trial register | What Should be the Next Vasopressor for Severe Septic Shock? Methylene Blue or Terlipressin | last verified some time ago; the register no longer confirms its status | - | 2017-01-31 | - |
| NCT03608514 Trial register | Terlipressin Alone Versus the Standard Therapy With Catecholamines for Hepatic Patients With Septic Shock- Prospective Single Center Randomized Controlled Study | last verified some time ago; the register no longer confirms its status | - | 2018-08-01 | - |
| NCT03530761 Trial register | Korean Cohort Study of AKI & HRS in Cirrhosis | last verified some time ago; the register no longer confirms its status | - | 2018-04-25 | - |
| NCT01921985 Trial register | Terlipressin Administration in Patients Undergoing Major Liver Resection | terminated before completion | - | 2013-08-14 | - |
| NCT03477461 Trial register | Effects of Terlipressin on Management of Potential Organ Donors | completed | - | 2018-03-26 | - |
| NCT00966355 Trial register | Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding | completed | - | 2009-08-26 | Posted |
| NCT02364297 Trial register | TIPS in Fundal Variceal Bleeding (the TFB Study) | last verified some time ago; the register no longer confirms its status | - | 2015-02-05 | - |
| NCT02788240 Trial register | To Study the Influence of GCSF on Natural History of Acute On Chronic Liver Failure After the Acute Phase | terminated before completion | - | 2016-06-02 | - |
| NCT02588716 Trial register | Effects of Terlipressin on Blood Loss and Transfusion Requirements During Major Liver Resection. | completed | - | 2015-10-28 | - |
| NCT02718599 Trial register | Effect of Terlipressin Infusion on Systemic and Hepatic Hemodynamics During Hepatobiliary Surgery | completed | - | 2016-03-24 | - |
| NCT03352349 Trial register | Effect of Terlipressinum on the Portal Vein Pressure of Patients With Liver Tumor After Liver Resection | last verified some time ago; the register no longer confirms its status | - | 2017-11-24 | - |
| NCT02573727 Trial register | To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure | completed | - | 2015-10-12 | - |
| NCT02468063 Trial register | To Assess the Efficacy of Early Introduction of a Combination of Low Dose Vasopressin Analogue in Addition to Noradrenaline as a Vasopressor in Patients of Cirr | completed | - | 2015-06-10 | - |
| NCT00089570 Trial register | Study of Terlipressin Versus Placebo to Treat Hepatorenal Syndrome Type 1 | completed | - | 2004-08-09 | - |
| NCT02368249 Trial register | Does Terlipressin Improve Renal Outcome After Liver Surgery | withdrawn before enrolling anyone | - | 2015-02-23 | - |
| NCT01278199 Trial register | Bronchial Artery Embolization and Medical Measures in Non Severe Acute Hemoptysis of Mild-moderate Abundance | completed | - | 2011-01-14 | - |
| NCT02059460 Trial register | Perioperative Evaluation of Terlipressin Infusion During Living Donor Liver Transplantation on Incidence of Acute Kidney | completed | - | 2014-02-11 | - |
| NCT01836224 Trial register | Efficacy and Safety of Monotherapy With Noradrenaline and Terlipressin in Patients of Cirrhosis With Septic Shock Admitted to Intensive Care Unit | completed | - | 2013-04-19 | - |
| NCT01649037 Trial register | To Compare the Efficacy of Nor Adrenaline and Terlipressin vs Step up Terlipressin Therapy in Hepatorenal Syndrome | withdrawn before enrolling anyone | - | 2012-07-25 | - |
| NCT01530711 Trial register | Treatment of Hepatorenal Syndrome With Terlipressin Infusion Adjusted to Hemodynamic Response | last verified some time ago; the register no longer confirms its status | - | 2012-02-10 | - |
| NCT02119884 Trial register | Hemodynamic Effects of Terlipressin and High Dose Octreotide | completed | - | 2014-04-22 | - |
| NCT02757703 Trial register | Vasoactive Drugs in Real World Practice | completed | - | 2016-05-02 | - |
| NCT01640964 Trial register | An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal Hypertension | completed | - | 2012-07-16 | Posted |
| NCT00628160 Trial register | Terlipressin in Septic Shock in Cirrhosis | completed | - | 2008-03-04 | - |
| NCT01631890 Trial register | To Compare the Efficacy of Endoscopic Ultrasound Assisted Endoscopic Glue Injection and Conventional Endoscopic Injection Therapy for Prevention of Gastric Vari | withdrawn before enrolling anyone | - | 2012-06-14 | - |
| NCT02489864 Trial register | The Effect of Terlipressin in the Prevention of Type 2 Hepatorenal Syndrome by Improving Mean Arterial Pressure | last verified some time ago; the register no longer confirms its status | - | 2015-07-03 | - |
| NCT00986817 Trial register | Terlipressin in Cirrhotic Patients With Recidivation Ascites Treated With Paracentesis and Albumin | completed | - | 2009-09-30 | - |
| NCT01697410 Trial register | Continuos Terlipressin Infusion in Septic Shock | last verified some time ago; the register no longer confirms its status | - | 2012-10-02 | - |
| NCT02306239 Trial register | The Effect of Terlipressin on Intesitnal Function in Septic Shock Patients | last verified some time ago; the register no longer confirms its status | - | 2014-12-03 | - |
| NCT02311608 Trial register | Effects of Terlipressin When Usual Somatostatin or Octreotide Dose Fails | last verified some time ago; the register no longer confirms its status | - | 2014-12-08 | - |
| NCT00742339 Trial register | Terlipressin + Albumin Versus Midodrine + Octreotide in the Treatment of Hepatorenal Syndrome | terminated before completion | - | 2008-08-27 | - |
| NCT00742690 Trial register | Terlipressin Given As I.V. Boluses Versus Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome | last verified some time ago; the register no longer confirms its status | - | 2008-08-28 | - |
| NCT01271114 Trial register | Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension | terminated before completion | - | 2011-01-06 | - |
| NCT01932151 Trial register | Treatment of Type-1 Hepatorenal Syndrome Associated With Sepsis | completed | - | 2013-08-30 | - |
| NCT01079715 Trial register | Safety and Efficacy of Propranolol in Newborns With Retinopathy of Prematurity | completed | - | 2010-03-02 | - |
| NCT01335516 Trial register | Follow-up of Glypressin (Terlipressin) Clinical Efficacy in the Treatment of Bleeding Oesophageal Varices | completed | - | 2011-04-14 | - |
| NCT01637454 Trial register | TYPE 2 HEPATORENAL SYNDROME | completed | - | 2012-07-11 | - |
| NCT01373606 Trial register | A Study of Terlipressin in Patients With Hepatorenal Syndrome Type 1 | completed | - | 2011-06-15 | - |
| NCT01112852 Trial register | EVL (Endoscopic Variceal Ligation) Plus Vasoconstrictor vs.Ligation Plus PPI( Proton Pump Inhibitor) in the Control of Acute Esophageal Variceal Bleeding | completed | - | 2010-04-28 | - |
| NCT00995839 Trial register | Terlipressin in Septic Shock: Effects on Microcirculation | completed | - | 2009-10-15 | - |
| NCT00863837 Trial register | Prevention of Esophageal Variceal Rebleeding | last verified some time ago; the register no longer confirms its status | - | 2009-03-18 | - |
| NCT00793559 Trial register | Terlipressin Administration in Septic Shock Refractory to Catecholamines | last verified some time ago; the register no longer confirms its status | - | 2008-11-19 | - |
| NCT00369694 Trial register | Short Course Terlipressin for Control of Acute Variceal Bleeding | completed | - | 2006-08-29 | - |
| NCT00370253 Trial register | Noradrenalin vs Terlipressin in Hepatorenal Syndrome | completed | - | 2006-08-31 | - |
| NCT00481572 Trial register | Continuous Infusion of Terlipressin in Septic Shock | completed | - | 2007-06-01 | - |
| NCT00534677 Trial register | The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed | completed | - | 2007-09-26 | - |
| NCT00287664 Trial register | Treatment of Hepatorenal Syndrome With Terlipressin Plus Albumin vs Albumin | suspended | - | 2006-02-07 | - |
| NCT00115947 Trial register | Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites | completed | - | 2005-06-27 | - |
Source: ClinicalTrials.gov and EU CTIS, read 2026-10-03. Not medical advice.
WEEKLY
Register Watch, weekly
New trials, approvals and enforcement actions. One email a week.