vasopressin analogue

Terlipressin updates

Answer

6 changes for Terlipressin in the last 12 months. Latest: 2026-08-05.

DateTypeWhat changedSource
2026-08-05TrialNew trial registered: Terlipressin vs Placebo to Reduce Bleeding in Fibroid SurgeryTrial register ClinicalTrials.gov
2026-07-22TrialNew trial registered: Intraoperative Continuous Terlipressin Infusion is Associated With Reduced Severe Postoperative Complications After Laparoscopic Hepatectomy: a ProsTrial register ClinicalTrials.gov
2026-06-19LabelFDA label revised: Terlivaz (NDA022231)Regulator FDA drug label register
2026-03-10TrialNew trial registered: Comparison of Terlipressin Versus Octreotide in Patients With Hepatorenal SyndromeTrial register ClinicalTrials.gov
2025-12-26TrialNew trial registered: Effects of Terlipressin and Somatostatin on Portal Pressure in Patients Undergoing Living Donor Liver TransplantationTrial register ClinicalTrials.gov
2025-11-26TrialNew trial registered: Terlipressin vs. Somatostatin in Cirrhotic Patients With Acute Variceal Bleeding and Renal DysfunctionTrial register ClinicalTrials.gov
2025-09-11TrialNew trial registered: Double Plasma Separation and Adsorption in Acute-on-Chronic Liver Failure (DPMAS-ACLF Trial)Trial register ClinicalTrials.gov
2025-07-11TrialNew trial registered: National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem Cell Therapy in Non-viral Acute on Chronic LiTrial register ClinicalTrials.gov
2025-07-11TrialNew trial registered: National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem-Cell (MSC) Therapy in Non-viral Acute on ChroTrial register ClinicalTrials.gov
2025-03-04TrialNew trial registered: Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney TransplantationTrial register ClinicalTrials.gov
2025-02-07TrialNew trial registered: Efficacy and Safety of Continuous Infusion of Terlipressin vs Bolus Terlipressin in ACLF Patients With Acute Esophageal Variceal BleedTrial register ClinicalTrials.gov
2024-10-09ResultsResults posted: Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE)Trial register ClinicalTrials.gov
2024-08-16TrialNew trial registered: Safety and Efficacy of Continuous Infusion of Terlipressin With Norepinephrine Versus Norepinephrine Alone in Improving Outcomes of Acute Kidney InjTrial register ClinicalTrials.gov
2024-02-28RecallFDA recall, Class II: Mallinckrodt Hospital Products Inc.. cGMP deviations: Temperature excursion due to shipping delay from manufacturer to distributor. Affected distribRegulator FDA enforcement reports
2024-02-16Federal RegisterFederal Register notice: Product-Specific Guidances; Draft and Revised Draft Guidances for Industry; AvailabilityRegulator Federal Register
2024-02-13TrialNew trial registered: Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal SyndromeTrial register ClinicalTrials.gov
2023-12-08TrialNew trial registered: Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal DiseaseTrial register ClinicalTrials.gov
2023-11-03TrialNew trial registered: Preemptive TIPS for Variceal Bleeding in Cirrhotic Patients With Occlusive Portal Vein ThrombosisTrial register ClinicalTrials.gov
2023-11-03TrialNew trial registered: Preemptive TIPS for Gastric Variceal Bleeding in Patients With CirrhosisTrial register ClinicalTrials.gov
2023-10-31TrialNew trial registered: Effect of Terlipressin on the Incidence of Early Postoperative Acute Kidney Injury in Liver Transplantation PatientsTrial register ClinicalTrials.gov
2023-09-07TrialNew trial registered: Efficacy of Continuous Terlipressin Therapy After Endoscopic Variceal LigationTrial register ClinicalTrials.gov
2023-05-25TrialNew trial registered: Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal SyndromeTrial register ClinicalTrials.gov
2023-04-10TrialNew trial registered: Methods Decreasing Bleeding in Open MyomectomyTrial register ClinicalTrials.gov
2023-03-07TrialNew trial registered: Noradrenaline Versus Glypressin for Prevention of Hypotension After Deflation of Tourniquet in Knee ArthroplastyTrial register ClinicalTrials.gov
2023-01-26TrialNew trial registered: To Study the Hemodynamic Response of Early Addition of Carvedilol to Terlipressin in Acute Variceal Bleed in Child's B and C CirrhosisTrial register ClinicalTrials.gov
2022-11-29ResultsResults posted: A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With TerlipressinTrial register ClinicalTrials.gov
2022-08-18ResultsResults posted: Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1Trial register ClinicalTrials.gov
2022-07-28TrialNew trial registered: Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver CirrhoticsTrial register ClinicalTrials.gov
2022-06-13TrialNew trial registered: Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Hepatorenal Syndrome-AcuTrial register ClinicalTrials.gov
2022-04-18TrialNew trial registered: Comparison of Endoscopic Band Ligation Plus 24-hour Versus 72-hour Terlipressin TherapyTrial register ClinicalTrials.gov
2022-04-07TrialNew trial registered: Efficacy and Safety of Vasopressin Versus Terlipressin as a Second Vasopressor in Critically Ill Cirrhotics With Septic Shock- the VITEL-C TrialTrial register ClinicalTrials.gov
2022-04-01TrialNew trial registered: HRS-AKI Treatment With TIPS in Patients With CirrhosisTrial register ClinicalTrials.gov
2022-03-04TrialNew trial registered: The Effect of Intramyometrial Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Open Myomectomy Operations Without UsiTrial register ClinicalTrials.gov
2022-02-16TrialNew trial registered: The Effect of Intramyometrial Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Open Myomectomy Operations Using HaemoTrial register ClinicalTrials.gov
2022-01-26TrialNew trial registered: Clinical Trial Comparing Noradrenaline (NA) Plus Placebo Versus Noradrenaline Plus Terlipressin (TP) in Septic ShockTrial register ClinicalTrials.gov
2021-12-27TrialNew trial registered: The Effect of Intracapsular Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Laparoscopic Myomectomy OperationsTrial register ClinicalTrials.gov
2021-12-13TrialNew trial registered: The Effect of Intramyometrial Injection of Terlipressin Versus Intramyometrial Injection of Carbitocin on Hemoglobin and Blood Loss During LaparoscoTrial register ClinicalTrials.gov
2021-10-15TrialNew trial registered: Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic PatientsTrial register ClinicalTrials.gov
2021-07-14TrialNew trial registered: ACid Tranexamic or Terlipressin for Initial Emergency Treatment of Mild to seVere hEmoptysis: a Randomized Trial.Trial register ClinicalTrials.gov
2021-07-13ResultsResults posted: Continuous Infusion Terlipressin for Patients With Cirrhosis and Refractory AscitesTrial register ClinicalTrials.gov
2021-07-01TrialNew trial registered: Effects of Terlipressin on Renal Perfusion in Patients With Septic ShockTrial register ClinicalTrials.gov
2021-03-29TrialNew trial registered: Comparison of Bolus Versus Continuous Infusion of Terlipressin Cirrhotic Patients With Septic Shock.Trial register ClinicalTrials.gov
2020-07-08Federal RegisterFederal Register notice: Cardiovascular and Renal Drugs Advisory Committee; Notice of Meeting; Establishment of a Public Docket; Request for CommentsRegulator Federal Register
2020-07-07TrialNew trial registered: Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE)Trial register ClinicalTrials.gov
2020-06-04TrialNew trial registered: Efficacy of Early Terlipressin Plus Albumin Therapy in Comparison to Standard Treatment for HRS-AKI in Acute-on-chronic Liver Failure.Trial register ClinicalTrials.gov
2020-04-22TrialNew trial registered: Terlipression Prevent Developing of Acute Kidney Injury During Upper-gastroentestinal BleedingTrial register ClinicalTrials.gov
2020-04-20TrialNew trial registered: Hemodynamic Profile of Terlipressin and Octreotide in Patients With Cirrhosis and Portal Hypertension. A Randomised, Single Blinded Clinical Trial.Trial register ClinicalTrials.gov
2020-04-09TrialNew trial registered: Terlipressin for Refractory Septic ShockTrial register ClinicalTrials.gov
2020-01-09TrialNew trial registered: The Effect of Terlipressin on Recovery of Liver Function After HepatectomyTrial register ClinicalTrials.gov
2019-10-01TrialNew trial registered: Methylene Blue Versus Vasopressin Analogue for Treatment of Septic Shock in Preterm NeonateTrial register ClinicalTrials.gov
2019-09-30TrialNew trial registered: A Study for Evaluation of BIV201 to Reduce Ascites and Complications in Patients With Cirrhosis and Refractory AscitesTrial register ClinicalTrials.gov
2019-08-14TrialNew trial registered: 2- Day vs. 5- Day Terlipressin and Ceftriaxone in the Control Acute Gastroesophageal Variceal HemorrhageTrial register ClinicalTrials.gov
2019-07-22TrialNew trial registered: Functional MRI-based Assessment of Terlipressin vs. Octreotide on Renal Function in Cirrhotic Patients With Acute Variceal Bleeding (CHESS1903)Trial register ClinicalTrials.gov
2019-07-22TrialNew trial registered: Terlipressin Infusion in Variceal HemorrhageTrial register ClinicalTrials.gov
2019-07-05TrialNew trial registered: Efficacy and Safety of Hemoperfusion or Plasma Exchange Compared to Standard Medical Therapy in Patients With Acute on Chronic Liver FailureTrial register ClinicalTrials.gov
2019-05-16ResultsResults posted: Decision Support for Intraoperative Low Blood PressureTrial register ClinicalTrials.gov
2019-02-19TrialNew trial registered: Terlipressin on Effect of Renal Function in Cirrhotic Patients With Acute Gastrointestinal HemorrhageTrial register ClinicalTrials.gov
2019-01-30TrialNew trial registered: Terlipressin Infusion Alone Vs Terlipressin With Noradrenaline Infusion In The Treatment of Hepatorenal Syndrome Type 1Trial register ClinicalTrials.gov
2018-08-01TrialNew trial registered: Terlipressin Alone Versus the Standard Therapy With Catecholamines for Hepatic Patients With Septic Shock- Prospective Single Center Randomized ContTrial register ClinicalTrials.gov
2018-07-12TrialNew trial registered: Efficacy of Terlipressin Therapy in Acute Variceal Haemorrhage After EVLTrial register ClinicalTrials.gov
2018-06-28TrialNew trial registered: Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion NeedsTrial register ClinicalTrials.gov
2018-04-25TrialNew trial registered: Korean Cohort Study of AKI & HRS in CirrhosisTrial register ClinicalTrials.gov
2018-03-30TrialNew trial registered: MRI to Assess the Effect of Terlipressin in Patients With Acute Hepatorenal Syndrome (HRS-AKI)Trial register ClinicalTrials.gov
2018-03-26TrialNew trial registered: Effects of Terlipressin on Management of Potential Organ DonorsTrial register ClinicalTrials.gov
2018-03-19ResultsResults posted: Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal BleedingTrial register ClinicalTrials.gov
2018-01-10TrialNew trial registered: Effect of Terlipressin on Cerebral Oxygen Saturation During Liver TransplantationTrial register ClinicalTrials.gov
2017-11-24TrialNew trial registered: Effect of Terlipressinum on the Portal Vein Pressure of Patients With Liver Tumor After Liver ResectionTrial register ClinicalTrials.gov
2017-11-08TrialNew trial registered: Evaluation of Early Association of Terlipressin and Norepinephrine During Septic Shock; the TerliNor StudyTrial register ClinicalTrials.gov
2017-09-08TrialNew trial registered: Thermal Imaging in Liver Disease.Trial register ClinicalTrials.gov
2017-05-09TrialNew trial registered: Efficacy and Safety of Terlipressin With Albumin Versus Midodrine With Albumin Versus Albumin Alone in Prevention of Paracentesis Induced CirculatorTrial register ClinicalTrials.gov
2017-04-26TrialNew trial registered: Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver CirrhosisTrial register ClinicalTrials.gov
2017-04-20TrialNew trial registered: To Assess the Efficacy of High-Volume Plasma Exchange and GCSF Versus GCSF Alone in Patients of Acute on Chronic Liver Failure (ACLF).Trial register ClinicalTrials.gov
2017-04-11TrialNew trial registered: Continuous Infusion Terlipressin for Patients With Cirrhosis and Refractory AscitesTrial register ClinicalTrials.gov
2017-01-31TrialNew trial registered: What Should be the Next Vasopressor for Severe Septic Shock? Methylene Blue or TerlipressinTrial register ClinicalTrials.gov
2016-11-21TrialNew trial registered: Interest of in Situ Terlipressin Administration Before the Realisation of Bronchial BiopsyTrial register ClinicalTrials.gov
2016-06-02TrialNew trial registered: To Study the Influence of GCSF on Natural History of Acute On Chronic Liver Failure After the Acute PhaseTrial register ClinicalTrials.gov
2016-05-12TrialNew trial registered: Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1Trial register ClinicalTrials.gov
2016-05-02TrialNew trial registered: Vasoactive Drugs in Real World PracticeTrial register ClinicalTrials.gov
2016-04-04TrialNew trial registered: Decision Support for Intraoperative Low Blood PressureTrial register ClinicalTrials.gov
2016-03-24TrialNew trial registered: Effect of Terlipressin Infusion on Systemic and Hepatic Hemodynamics During Hepatobiliary SurgeryTrial register ClinicalTrials.gov
2016-03-01TrialNew trial registered: To Assess Safety and Efficacy of Bolus Versus Continuous Infusion of Terlipressin in Acute Variceal BleedingTrial register ClinicalTrials.gov
2016-01-20ResultsResults posted: An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal HypertensionTrial register ClinicalTrials.gov
2015-10-28TrialNew trial registered: Effects of Terlipressin on Blood Loss and Transfusion Requirements During Major Liver Resection.Trial register ClinicalTrials.gov
2015-10-12TrialNew trial registered: To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver FailureTrial register ClinicalTrials.gov
2015-07-03TrialNew trial registered: The Effect of Terlipressin in the Prevention of Type 2 Hepatorenal Syndrome by Improving Mean Arterial PressureTrial register ClinicalTrials.gov
2015-06-10TrialNew trial registered: To Assess the Efficacy of Early Introduction of a Combination of Low Dose Vasopressin Analogue in Addition to Noradrenaline as a Vasopressor in PatiTrial register ClinicalTrials.gov
2015-06-08TrialNew trial registered: Efficacy Of Bovine Colostrum In The Treatment Of Severe Alcohol-Associated Hepatitis: A Randomized Controlled TrialTrial register ClinicalTrials.gov
2015-02-23TrialNew trial registered: Does Terlipressin Improve Renal Outcome After Liver SurgeryTrial register ClinicalTrials.gov
2015-02-05TrialNew trial registered: Early Use of TIPSS in Patients With Cirrhosis and Variceal BleedingTrial register ClinicalTrials.gov
2015-02-05TrialNew trial registered: TIPS in Fundal Variceal Bleeding (the TFB Study)Trial register ClinicalTrials.gov
2014-12-08TrialNew trial registered: Effects of Terlipressin When Usual Somatostatin or Octreotide Dose FailsTrial register ClinicalTrials.gov
2014-12-03TrialNew trial registered: The Effect of Terlipressin on Intesitnal Function in Septic Shock PatientsTrial register ClinicalTrials.gov
2014-04-22TrialNew trial registered: Hemodynamic Effects of Terlipressin and High Dose OctreotideTrial register ClinicalTrials.gov
2014-02-11TrialNew trial registered: Perioperative Evaluation of Terlipressin Infusion During Living Donor Liver Transplantation on Incidence of Acute KidneyTrial register ClinicalTrials.gov
2013-08-30TrialNew trial registered: Treatment of Type-1 Hepatorenal Syndrome Associated With SepsisTrial register ClinicalTrials.gov
2013-08-14TrialNew trial registered: Terlipressin Administration in Patients Undergoing Major Liver ResectionTrial register ClinicalTrials.gov
2013-04-19TrialNew trial registered: Efficacy and Safety of Monotherapy With Noradrenaline and Terlipressin in Patients of Cirrhosis With Septic Shock Admitted to Intensive Care UnitTrial register ClinicalTrials.gov
2012-10-02TrialNew trial registered: Continuos Terlipressin Infusion in Septic ShockTrial register ClinicalTrials.gov
2012-07-25TrialNew trial registered: To Compare the Efficacy of Nor Adrenaline and Terlipressin vs Step up Terlipressin Therapy in Hepatorenal SyndromeTrial register ClinicalTrials.gov
2012-07-16TrialNew trial registered: An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal HypertensionTrial register ClinicalTrials.gov

The 100 newest of 126 are listed.

From ClinicalTrials.gov, EU CTIS, FDA labels, recalls, shortages and warning letters, the Federal Register, and regulators' published actions. Not medical advice.

WEEKLY

Register Watch, weekly

New trials, approvals and enforcement actions. One email a week.