GLP-1 receptor agonist

Semaglutide updates

Answer

307 changes for Semaglutide in the last 12 months. Latest: 2026-10-02.

DateTypeWhat changedSource
2026-10-02TrialNew trial registered: A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (ZenagaTrial register ClinicalTrials.gov
2026-09-30TrialNew trial registered: Study on the Efficacy and Safety of Initial Combination of Finerenone and Semaglutide in Non-Diabetic Adult Patients With Obesity Complicated by ChrTrial register ClinicalTrials.gov
2026-09-30TrialNew trial registered: Real-World Patient and Physician Experience With Semaglutide Across Six Emerging MarketsTrial register ClinicalTrials.gov
2026-09-29ResultsResults posted: Phase 2a Placebo-Controlled Study of VTX3232 Alone or in Combination With Semaglutide in ObesityTrial register ClinicalTrials.gov
2026-09-29TrialNew trial registered: A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Trial register ClinicalTrials.gov
2026-09-29TrialNew trial registered: A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body WeightTrial register ClinicalTrials.gov
2026-09-29TrialNew trial registered: SEMAFORCRANIO : Multicenter, Double-blind, Parallel, Randomized Controlled Trial of the Efficacy of Semaglutide in Hypothalamic Obesity Secondary toTrial register ClinicalTrials.gov
2026-09-25TrialNew trial registered: Evaluate the Safety and Tolerability of Multiple Doses of JMT206 Injection in Obese ParticipantsTrial register ClinicalTrials.gov
2026-09-23TrialNew trial registered: A Study Comparing the Effects of BGM0504 Injection and Semaglutide Injection on Obese Subjects.Trial register ClinicalTrials.gov
2026-09-18Warning letterFDA warning letter to Empower Clinic Services, LLC dba Empower Pharmacy: CGMP/Finished Pharmaceuticals/Adulterated/Unapproved New DrugRegulator FDA warning letters
2026-09-15ResultsResults posted: A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With MetforminTrial register ClinicalTrials.gov
2026-09-15TrialNew trial registered: Semaglutide, Weight Loss, and LNG-IUD for Conservative Treatment of Endometrial Atypical Hyperplasia and Grade 1 Endometrial CancerTrial register ClinicalTrials.gov
2026-09-15TrialNew trial registered: Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical TrialTrial register ClinicalTrials.gov
2026-09-14TrialNew trial registered: Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to CagrisemaTrial register ClinicalTrials.gov
2026-09-14TrialNew trial registered: Optimizing Albuminuria Treatment in CKD With Finerenone and SemaglutideTrial register ClinicalTrials.gov
2026-09-10TrialNew trial registered: A Study Evaluating Safety and Tolerability of Switching From Semaglutide to Zovaglutide in Adults With Obesity (HORIZON-SWITCH-SZ)Trial register ClinicalTrials.gov
2026-09-03TrialNew trial registered: Phase 2 Clinical Study of MWN109 Tablets in Participants With Type 2 Diabetes MellitusTrial register ClinicalTrials.gov
2026-09-01TrialNew trial registered: Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes MellitusTrial register ClinicalTrials.gov
2026-08-31ResultsResults posted: Body Surface Gastric Mapping in Patients on SemaglutideTrial register ClinicalTrials.gov
2026-08-25TrialNew trial registered: A Randomized Controlled Study of Dose-tapering Regimen of Semaglutide for Weight-Loss Maintenance in Adults With Overweight or ObesityTrial register ClinicalTrials.gov
2026-08-24Warning letterFDA warning letter to NuScience Peptides LLC: Unapproved New Drugs/MisbrandedRegulator FDA warning letters
2026-08-24Warning letterFDA warning letter to Peak Performance Peptides: Unapproved New Drugs/MisbrandedRegulator FDA warning letters
2026-08-24Warning letterFDA warning letter to Peptide Partners LLC: Unapproved New Drugs/MisbrandedRegulator FDA warning letters
2026-08-24Warning letterFDA warning letter to Royal Peptides LLC: Unapproved New Drugs/MisbrandedRegulator FDA warning letters
2026-08-24Warning letterFDA warning letter to TXP Innovations LLC dba Tex Peptides: Unapproved New Drugs/MisbrandedRegulator FDA warning letters
2026-08-21ResultsResults posted: A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 DiabetesTrial register ClinicalTrials.gov
2026-08-21TrialNew trial registered: OBESIAL: A Prospective Interventional Real-world Study of a Multidisciplinary Obesity Management ProgrammeTrial register ClinicalTrials.gov
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19RecallFDA recall, Class II: Apollo Care, LLC. Presence of Particulate Matter; identified as a nylon/polyamide and silk/proteinaceous-type materialRegulator FDA enforcement reports
2026-08-19TrialNew trial registered: A Retrospective Real-World Cohort StudyTrial register ClinicalTrials.gov
2026-08-19TrialNew trial registered: Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use OutcomesTrial register ClinicalTrials.gov
2026-08-18TrialNew trial registered: Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body WeightTrial register ClinicalTrials.gov
2026-08-18TrialNew trial registered: GLP-1/GIP Receptor Agonists in Obesity-Related HFpEF: The GLIDE-HF RegistryTrial register ClinicalTrials.gov
2026-08-18TrialNew trial registered: Semaglutide in Youth With Autism Spectrum DisorderTrial register ClinicalTrials.gov
2026-08-18TrialNew trial registered: Efficacy and Safety of Semaglutide Versus Placebo on Cardiometabolic Profile in Patients With Schizophrenia With Metabolic SyndromeTrial register ClinicalTrials.gov
2026-08-17TrialNew trial registered: A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or ObesityTrial register ClinicalTrials.gov
2026-08-17TrialNew trial registered: Semaglutide and Structured Lifestyle Support to Improve Heart and Blood Vessel Health in Postmenopausal Obese Breast Cancer Survivors Taking AromataTrial register ClinicalTrials.gov
2026-08-14ResultsResults posted: Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in East Asian People Who Are Overweight or Living With ObesityTrial register ClinicalTrials.gov
2026-08-12TrialNew trial registered: HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting SemaglutideTrial register ClinicalTrials.gov
2026-08-10ResultsResults posted: A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)Trial register ClinicalTrials.gov
2026-08-10TrialNew trial registered: Evaluating the Efficacy and Safety of LUM-201 Plus Semaglutide Versus Semaglutide Plus Placebo in Older Obese AdultsTrial register ClinicalTrials.gov
2026-08-07TrialNew trial registered: Comparing Facial Aging Between Identical Twins With 3D ImagingTrial register ClinicalTrials.gov
2026-08-04TrialNew trial registered: A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body WeightTrial register ClinicalTrials.gov
2026-08-04TrialNew trial registered: A Study of BGM0504 in Early T2DM With ObesityTrial register ClinicalTrials.gov
2026-08-03ResultsResults posted: Semaglutide Treatment, Appetite, and Eating Behavior: Long-term EffectsTrial register ClinicalTrials.gov
2026-08-03TrialNew trial registered: GLP-1s in Hip and Knee ArthroplastyTrial register ClinicalTrials.gov
2026-07-31TrialNew trial registered: Tirzepatide Impact Assessment StudyTrial register ClinicalTrials.gov
2026-07-30LabelFDA label revised: Ozempic (NDA209637)Regulator FDA drug label register
2026-07-29Federal RegisterFederal Register notice: Product-Specific Guidances; Revised Draft Guidances for Industry; AvailabilityRegulator Federal Register
2026-07-28TrialNew trial registered: Semaglutide for Low Back PainTrial register ClinicalTrials.gov
2026-07-28TrialNew trial registered: Efficacy of Once Weekly Semaglutide in Patients With Type 2 Diabetes: a Non Randomized Clinical TrialTrial register ClinicalTrials.gov
2026-07-28TrialNew trial registered: Effects of Semaglutide on Brain Dopamine Responses to Food Cues in Adults With Obesity and Food Addiction TendenciesTrial register ClinicalTrials.gov
2026-07-27TrialNew trial registered: Myocardial Metabolic Flux in Pulmonary Arterial HypertensionTrial register ClinicalTrials.gov
2026-07-27TrialNew trial registered: Preoperative Semaglutide Prior to Radical ProstatectomyTrial register ClinicalTrials.gov
2026-07-27TrialNew trial registered: A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With ObesityTrial register ClinicalTrials.gov
2026-07-24TrialNew trial registered: A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) aTrial register ClinicalTrials.gov
2026-07-22TrialNew trial registered: Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist TherapyTrial register ClinicalTrials.gov
2026-07-20TrialNew trial registered: Efficacy and Safety of Mazdutide in Patients With Type 2 Diabetes Mellitus and Moderate to Severe Nonalcoholic Fatty Liver Disease Previously TreateTrial register ClinicalTrials.gov
2026-07-19TrialNew trial registered: Bariatric Surgery Combined With GLP-1RA: A Multicenter Study.Trial register ClinicalTrials.gov
2026-07-17TrialNew trial registered: Effects of GLP-1 RAs on Human Lactation OutcomesTrial register ClinicalTrials.gov
2026-07-14TrialNew trial registered: Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor AgonistsTrial register ClinicalTrials.gov
2026-07-14TrialNew trial registered: Salivary Function and Dental Changes During GLP-1 TherapyTrial register ClinicalTrials.gov
2026-07-14TrialNew trial registered: Can Two Dietary Interventions Maintain Weight Loss for 12 Months After GLP-1 Therapy in Adults With Overweight/Obesity?Trial register ClinicalTrials.gov
2026-07-14TrialNew trial registered: Non-Invasive Hepatic and Metabolic Index Changes After Incretin Therapy in Overweight/ObesityTrial register ClinicalTrials.gov
2026-07-10TrialNew trial registered: Pragmatic Trial to Study the Cost-Effectiveness of MyPhenome-RX Test to Guide Anti-Obesity PharmacotherapyTrial register ClinicalTrials.gov
2026-07-10TrialNew trial registered: Imaging in Semaglutide StudyTrial register ClinicalTrials.gov
2026-07-02ResultsResults posted: Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 AgonistsTrial register ClinicalTrials.gov
2026-07-01TrialNew trial registered: Free Fatty Acid Effects In Type 2 DiabetesTrial register ClinicalTrials.gov
2026-06-29TrialNew trial registered: Semaglutide Delivered Epi-Intradermally by Microarray Patch (VX-201) Versus Subcutaneous Administration in Healthy Overweight and Obese ParticipantsTrial register ClinicalTrials.gov
2026-06-26Federal RegisterFederal Register notice: List of Bulk Drug Substances for Which There Is a Clinical Need Under Section 503B of the Federal Food, Drug, and Cosmetic Act; Extension of CommRegulator Federal Register
2026-06-25TrialNew trial registered: A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to SemaglutideTrial register ClinicalTrials.gov
2026-06-25TrialNew trial registered: A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 DiabetesTrial register ClinicalTrials.gov
2026-06-24TrialNew trial registered: GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National Target Trial EmulationTrial register ClinicalTrials.gov
2026-06-23TrialNew trial registered: A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already UTrial register ClinicalTrials.gov
2026-06-17TrialNew trial registered: Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor ThTrial register ClinicalTrials.gov
2026-06-17TrialNew trial registered: Precision Obesity Medicine: Genetic Prediction of Response to GLP-1/GIP Agonists.Trial register ClinicalTrials.gov
2026-06-16TrialNew trial registered: Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's DiseaseTrial register ClinicalTrials.gov
2026-06-11TrialNew trial registered: Glucagon-Like Peptide-1 Receptor Agonists to Attenuate Metabolic Risk in Individuals With Duchenne Muscular DystrophyTrial register ClinicalTrials.gov
2026-06-10TrialNew trial registered: A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With ObesityTrial register ClinicalTrials.gov
2026-06-08TrialNew trial registered: GLP-1 Therapy After Bariatric Surgery in Chinese Patients With ObesityTrial register ClinicalTrials.gov
2026-06-08Warning letterFDA warning letter to Altru Telehealth, LLC dba Altru Telehealth: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to Amie Health, Inc. dba Amie: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to Clover Meds LLC dba Clover Meds: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to D&H Medical Services: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to Eden Health International Inc. dba Eden: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to Ezra Holdco LLC dba Ezra: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to FITISH: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to FitRX, LLC dba AM RX: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to Glow Medispa, LLC dba Mint Med: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to HydraMed IV LLC dba HydraMed: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters
2026-06-08Warning letterFDA warning letter to Joi and Blokes dba Joi + Blokes: False & Misleading Claims/Misbranded (Telehealth)Regulator FDA warning letters

The 100 newest of 1,089 are listed.

From ClinicalTrials.gov, EU CTIS, FDA labels, recalls, shortages and warning letters, the Federal Register, and regulators' published actions. Not medical advice.

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